Compile Data Set for Download or QSAR
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TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human HDAC9 using pan-HDAC substrate incubated for 3 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM162865(US9056843, 156)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50563276(CHEMBL4751615)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human recombinant HDAC9 using Boc-Lys(triflouroacetyI)-AMC substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM29589(Panobinostat | Faridak | LBH-589B | LBH-589 | US10...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human HDAC9 (604-1066 residues) expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant full length human HDAC9 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM19428(NVP-LAQ824 | (2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM162846(US9056843, 137)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272075((S)-1-(2,6-Difluorophenyl)-5-(3-fluoro-2- methylph...)
Affinity DataIC50: 12nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272075((S)-1-(2,6-Difluorophenyl)-5-(3-fluoro-2- methylph...)
Affinity DataIC50: 12nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM162846(US9056843, 137)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272071((S)-1-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...)
Affinity DataIC50: 15nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272078((S)-1-(2-Chloro-6-fluorophenyl)-5-(3-fluoro-2- met...)
Affinity DataIC50: 15nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272071((S)-1-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...)
Affinity DataIC50: 15nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272078((S)-1-(2-Chloro-6-fluorophenyl)-5-(3-fluoro-2- met...)
Affinity DataIC50: 15nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50563276(CHEMBL4751615)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human HDAC9 using Ac-LGK(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272067((S)-5-(3-Fluoro-2-methylphenyl)-l-(2-fluorophenyl)...)
Affinity DataIC50: 17nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272074((S)-1-(3-Chloro-2-fluorophenyl)-5-(3-fluoro-2- met...)
Affinity DataIC50: 17nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272067((S)-5-(3-Fluoro-2-methylphenyl)-l-(2-fluorophenyl)...)
Affinity DataIC50: 17nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272074((S)-1-(3-Chloro-2-fluorophenyl)-5-(3-fluoro-2- met...)
Affinity DataIC50: 17nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272079((S)-5-(3-Fluoro-2-methylphenyl)-1-(2-fluoro-6- met...)
Affinity DataIC50: 19nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272079((S)-5-(3-Fluoro-2-methylphenyl)-1-(2-fluoro-6- met...)
Affinity DataIC50: 19nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 19.4nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC9 by in vitro deacetylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human HDAC9 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant HDAC9 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50563273(CHEMBL4748500)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC9 using Ac-LGK(TFA)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272076((S)-1-(2,5-Dimethylphenyl)-5-(3-fluoro-2- methylph...)
Affinity DataIC50: 21nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272076((S)-1-(2,5-Dimethylphenyl)-5-(3-fluoro-2- methylph...)
Affinity DataIC50: 21nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272066((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-l-(o- to...)
Affinity DataIC50: 23nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272066((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-l-(o- to...)
Affinity DataIC50: 23nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50: 23.2nMAssay Description:Inhibition of human recombinant HDAC9 using trifluoroacetyl lysine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50044641(CHEMBL3311465)
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272077((S)-1-(2,6-Dimethylphenyl)-5-(3-fluoro-2- methylph...)
Affinity DataIC50: 27nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272158((R)-1-Benzyl-4-(3-fluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50: 27nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272077((S)-1-(2,6-Dimethylphenyl)-5-(3-fluoro-2- methylph...)
Affinity DataIC50: 27nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272158((R)-1-Benzyl-4-(3-fluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50: 27nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50304782(N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272065((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...)
Affinity DataIC50: 28nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272088((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(m- to...)
Affinity DataIC50: 28nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetHistone deacetylase 9(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM272065((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...)
Affinity DataIC50: 28nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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