Compile Data Set for Download or QSAR
Report error Found 807 of ic50 data for polymerid = 6027,50006186
LigandPNGBDBM50042053(CHEMBL3360172)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50042036(CHEMBL3360170)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50032547(CHEMBL3354181)
Affinity DataIC50: 1nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50042037(CHEMBL3360169)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50042035(CHEMBL3360171)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM116309(US8637528, OM69)
Affinity DataIC50: 1.30nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50381287(CHEMBL2019020)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068283(CHEMBL3403371)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140128(US8901315, 256)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50032540(CHEMBL3354179)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50032540(CHEMBL3354179)
Affinity DataIC50: 2nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50042039(CHEMBL3360167)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50032543(CHEMBL3354180)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068285(CHEMBL3403372)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50397056(CHEMBL2171440)
Affinity DataIC50: 3nMAssay Description:Inhibition of cloned human recombinant PDE7A assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140095(US8901315, 179)
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140100(US8901315, 190)
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50151638(8''-chloro-5''-(5-hydroxy-1,2,4-oxadiazol-3-ylmeth...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human PDE7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50042038(CHEMBL3360168)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50151562(7-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140142(US8901315, 275)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50151635(8''-chloro-5''-(1H-1,2,3,4-tetraazol-5-ylmethoxy)s...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PDE7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50381291(CHEMBL2019104)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50032600(CHEMBL3354171)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068277(CHEMBL3403358)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140168(US8901315, 373)
Affinity DataIC50: 4.5nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50068261(CHEMBL3403361)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50032529(CHEMBL3354178)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140155(US8901315, 341)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50032471(CHEMBL3354177)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068256(CHEMBL3403367)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50032607(CHEMBL3354175)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM116310(US8637528, OM056)
Affinity DataIC50: 5.67nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM140108(US8901315, 203)
Affinity DataIC50: 6.10nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50068282(CHEMBL3403360)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140099(US8901315, 188)
Affinity DataIC50: 6.5nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM140126(US8901315, 247)
Affinity DataIC50: 6.5nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM135582(US8846654, 111)
Affinity DataIC50: 6.70nMpH: 7.5Assay Description:The assay is carried out in 1.5 ml Eppendorf tubes comprising 40 mM of Tris-HCl (pH 7.5), 15 mM of MgCl2, 1 mM of EGTA, 0.5 mg/ml of bovine serum alb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM140098(US8901315, 184)
Affinity DataIC50: 6.80nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50068254(CHEMBL3403365)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50381296(CHEMBL2019109)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140169(US8901315, 375)
Affinity DataIC50: 7.20nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50032602(CHEMBL3354173)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human PDE7A1 expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068262(CHEMBL3403362)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM140121(US8901315, 237)
Affinity DataIC50: 7.80nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM140122(US8901315, 238)
Affinity DataIC50: 7.80nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM140068(US8901315, 112)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50381293(CHEMBL2019106)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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