Compile Data Set for Download or QSAR
Report error Found 188 of ic50 data for polymerid = 5850
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063701(2-(2-Iodo-phenylamino)-naphtho[2,3-d][1,3]oxazin-4...)
Affinity DataIC50: 200nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against purified human C1r protease proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063726(7-Chloro-2-(2,6-dichloro-phenylamino)-benzo[d][1,3...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063722(6,7-Dichloro-2-(2-iodo-phenylamino)-benzo[d][1,3]o...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50462100(CHEMBL4247936)
Affinity DataIC50: 600nMAssay Description:Inhibition of human plasma C1r using Cbz-Gly-Arg-S-Bzl as substrate preincubated for 10 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50289007(2-(2-Iodo-phenyl)-naphtho[2,3-d][1,3]oxazin-4-one ...)
Affinity DataIC50: 700nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063711(7-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075982(4-Methoxy-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063717(7-Chloro-2-(2-chloro-phenylamino)-benzo[d][1,3]oxa...)
Affinity DataIC50: 800nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063721(2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063717(7-Chloro-2-(2-chloro-phenylamino)-benzo[d][1,3]oxa...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50: 800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human serum C1r using AAME as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063724(2-(2,6-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063711(7-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063726(7-Chloro-2-(2,6-dichloro-phenylamino)-benzo[d][1,3...)
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063724(2-(2,6-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063732(2-(2-Chloro-phenylamino)-7-methyl-benzo[d][1,3]oxa...)
Affinity DataIC50: 900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.04E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease. More data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.37E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease. More data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063704(2-[(2-Iodo-phenyl)-methyl-amino]-benzo[d][1,3]oxaz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063732(2-(2-Chloro-phenylamino)-7-methyl-benzo[d][1,3]oxa...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063720(2-(2-Chloro-phenylamino)-7-nitro-benzo[d][1,3]oxaz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was evaluated for inhibitory activity against C1r serine protease in assay 1More data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50: 1.50E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075992(4-Guanidino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxaz...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50288998(6,7-Dichloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063697(2-(2,5-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 2.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063730(6,7-Dichloro-2-(2-chloro-phenylamino)-benzo[d][1,3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063697(2-(2,5-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 2.80E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075978(2-Bromo-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50289004(6-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50289016(5-Chloro-2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-o...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075992(4-Guanidino-N-methyl-N-(4-oxo-4H-benzo[d][1,3]oxaz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075986(N-Ethyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)-benz...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063715(2-(2-Iodo-phenylamino)-benzo[d][1,3]oxazin-4-one |...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075993(N-Methyl-N-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)-ben...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of purified human C1r protease.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50: 4.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063714(6-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063738(2-(2-Trifluoromethoxy-phenylamino)-benzo[d][1,3]ox...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50: 4.00E+3nMAssay Description:Evaluated in vitro for inhibitory activity against purified human C1r protease incubated in buffer for 60 minutesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50: 4.20E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50288996(2-(2-Trifluoromethyl-phenyl)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50289011(2-(2-Iodo-phenyl)-6-methoxy-benzo[d][1,3]oxazin-4-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063718(2-(2-Bromo-phenylamino)-benzo[d][1,3]oxazin-4-one ...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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