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Report error Found 103 of ic50 data for polymerid = 536,50000673
TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352285(US9802944, Example 1.13 | CHEM-US-00050)
Affinity DataIC50: 3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352340(US9802944, Example 2.01 | US11098048, Example 2.01)
Affinity DataIC50: 3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352353(US9802944, Example 2.1 | ((3aR,6aR)-hexahydropyrro...)
Affinity DataIC50: 3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352316(US9802944, Example 1.18 | CHEM-US-00055)
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352349(US9802944, Example 2.06 | US11098048, Example 2.06)
Affinity DataIC50: 4.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352280(US9802944, Example 1.09 | CHEM-US-00046)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352332(US9802944, Example 1.21 | BDBM352333 | CHEM-US-000...)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352366(US9802944, Example 2.23 | US11098048, Example 2.23)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352373(US9802944, Example 2.3 | 6-((3aR,6aR)-octahydropyr...)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352388(US9802944, Example 6 | ((3aR,8aS)-6-(2-Cyclopropyl...)
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352276(US9802944, Example 1.05 | CHEM-US-00042)
Affinity DataIC50: 6nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352309(US9802944, Example 1.16 | CHEM-US-00053)
Affinity DataIC50: 6nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352357(US9802944, Example 2.14 | US11098048, Example 2.14)
Affinity DataIC50: 6nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352364(US9802944, Example 2.21 | US11098048, Example 2.21)
Affinity DataIC50: 6nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352387(US9802944, Example 5.05)
Affinity DataIC50: 6nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352389(US9802944, Example 7 | 1H-Triazol-4-ylmethyl (3aS,...)
Affinity DataIC50: 6nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352277(US9802944, Example 1.06 | CHEM-US-00043)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352278(US9802944, Example 1.07 | CHEM-US-00044)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352325(US9802944, Example 1.19 | CHEM-US-00056)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352371(US9802944, Example 2.28 | US11098048, Example 2.28)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352372(US9802944, Example 2.29 | US11098048, Example 2.29)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352384(US9802944, Example 5.02)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352386(US9802944, Example 5.04)
Affinity DataIC50: 7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352275(US9802944, Example 1.04 | CHEM-US-00041)
Affinity DataIC50: 8nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352281(US9802944, Example 1.10 | CHEM-US-00047)
Affinity DataIC50: 8nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352274(US9802944, Example 1.03 | CHEM-US-00040)
Affinity DataIC50: 9nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352284(US9802944, Example 1.12 | CHEM-US-00049)
Affinity DataIC50: 9nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352286(US9802944, Example 1.14 | CHEM-US-00051)
Affinity DataIC50: 9nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352354(US9802944, Example 2.11 | US11098048, Example 2.11)
Affinity DataIC50: 9nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352360(US9802944, Example 2.17 | US11098048, Example 2.17)
Affinity DataIC50: 9nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352342(US9802944, Example 2.03 | US11098048, Example 2.03)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352350(US9802944, Example 2.07 | US9802944, Example 2.09 ...)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352356(US9802944, Example 2.13 | US11098048, Example 2.13)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352361(US9802944, Example 2.18 | US11098048, Example 2.18)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352362(US9802944, Example 2.19)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352365(US9802944, Example 2.22 | US11098048, Example 2.22)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352385(US9802944, Example 5.03)
Affinity DataIC50: 10nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352348(US9802944, Example 2.05 | US11098048, Example 2.05)
Affinity DataIC50: 10.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352355(US9802944, Example 2.12 | US11098048, Example 2.12)
Affinity DataIC50: 11nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352367(US9802944, Example 2.24 | US11098048, Example 2.24)
Affinity DataIC50: 11nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352358(US9802944, Example 2.15 | US11098048, Example 2.19)
Affinity DataIC50: 12nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352374(US9802944, Example 3 | 6-((3aS,6aS)-5-(5-Cycloprop...)
Affinity DataIC50: 12nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352338(US9802944, Example 1.23 | CHEM-US-00060)
Affinity DataIC50: 13nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352327(US9802944, Example 1.2 | (2-cyclopropyl-6-((tetrah...)
Affinity DataIC50: 14nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352332(US9802944, Example 1.21 | BDBM352333 | CHEM-US-000...)
Affinity DataIC50: 14nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352369(US9802944, Example 2.26 | US11098048, Example 2.26)
Affinity DataIC50: 14nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352282(US9802944, Example 1.11 | CHEM-US-00048)
Affinity DataIC50: 15nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352382(US9802944, Example 5 | ((3aR,6aR)-5-(2-Cyclopropyl...)
Affinity DataIC50: 16nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352383(US9802944, Example 5.01)
Affinity DataIC50: 16nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetAtaxin-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM352272(US9802944, Example 1.01 | CHEM-US-00038)
Affinity DataIC50: 17nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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