Compile Data Set for Download or QSAR
Report error Found 47 of ic50 data for polymerid = 5236
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.998nMAssay Description:Inhibition of human MRCKalpha using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM199250(US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human MRCKalpha using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human His-tagged CDC42BPA catalytic domain expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50256383(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 79nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50256163(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 210nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50311713(SR-6494 | N-(2-(dimethylamino)ethyl)-N-(3-methoxyb...)
Affinity DataIC50: 247nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50324578((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
Affinity DataIC50: 333nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM25473(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
Affinity DataIC50: 367nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50324574((R)-6-Methoxy-N-(2-((1-methylpiperidin-4-yl)methox...)
Affinity DataIC50: 669nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50324592((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
Affinity DataIC50: 810nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged CDC42BPA catalytic domain expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430333(CHEMBL2334288)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430359(CHEMBL2333894)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430374(CHEMBL2334292)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430373(CHEMBL2334293)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430371(CHEMBL2333905)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430370(CHEMBL2333906)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430368(CHEMBL2333908)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430357(CHEMBL2333896)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430377(CHEMBL2333898)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430376(CHEMBL2333882)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430348(CHEMBL2333884)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430345(CHEMBL2333887)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50315888(N-(3-(5-(2-(3-morpholinophenylamino)pyrimidin-4-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDC42BPAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 1.19E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM25474(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 1.19E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human His-tagged CDC42BPA catalytic domain expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50431137(CHEMBL2332060)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50431138(CHEMBL2332097)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50431135(CHEMBL2332065)
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM25470(cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...)
Affinity DataIC50: 4.85E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50324575((R)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4...)
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50431131(CHEMBL2332056)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM25471(N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodi...)
Affinity DataIC50: 7.05E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50311726(N-ethyl-N-(3-methoxybenzyl)-6-(1H-pyrazol-4-yl)ben...)
Affinity DataIC50: 7.86E+3nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50431134(CHEMBL2332068)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin) using LCD-AKRRRRLSSLRA-NH2 as substrate after 75 mins by luminescence assay in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human His-tagged CDC42BPA catalytic domain expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50311728(SR-6074 | 3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-...)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant His-tagged CDC42BPA catalytic domain (1 to 473 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50499634(CHEMBL3741589)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDC42BPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MRCKalpha using [KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK] as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MRCKalpha (1 to 473 residues) using KKRNRTLTV as substrate incubated for 40 mins in presence of [gamma-33ATP by radio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His-tagged MRCKalpha catalytic domain (1 to 473 residues) expressed in baculovirus expression system using serine/thr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed