Compile Data Set for Download or QSAR
Report error Found 593 of ic50 data for polymerid = 5134,5135,5931
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648297(US11884682, Compound 31 | 1-(3-methoxy-4-(((5-(thi...)
Affinity DataIC50: 6.92nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648295(US11884682, Compound 29 | 3'-methoxy-4'-((5-(thiop...)
Affinity DataIC50: 7.24nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50327348(3-(3-hydroxybenzyl)-6-methylbenzo[d]oxazol-2(3H)-o...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648298(US11884682, Compound 32 | 2-((3-metboxy-4-((5-(thi...)
Affinity DataIC50: 9.55nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50327346(3-(3-hydroxybenzyl)-5-methylbenzo[d]oxazol-2(3H)-o...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648281(US11884682, Compound 17 | 4-(2-hydroxyethoxy)-2-me...)
Affinity DataIC50: 10.5nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648291(US11884682, Compound 26 | 4-(3-(2H-tetrazol-5-yl)p...)
Affinity DataIC50: 11.2nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648286(US11884682, Compound 22 | 4-((2H-tetrazol-5-yl)met...)
Affinity DataIC50: 12.3nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648296(US11884682, Compound 30 | (3-methoxy-4-((5-(thioph...)
Affinity DataIC50: 12.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648260(US11884682, Compound 5 | 2,4-dimethoxy-N-(5-(thiop...)
Affinity DataIC50: 18.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648293(US11884682, Compound 27 | Cis-4-(3-methoxy-4-((5-(...)
Affinity DataIC50: 18.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648289(US11884682, Compound 25 | 4-(3-cyanopropyl)-2-meth...)
Affinity DataIC50: 20.9nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648267(US11884682, Compound 9 | 2,4-dimethoxy-N-(5-(thiop...)
Affinity DataIC50: 22.9nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648282(US11884682, Compound 18 | 4-(2-(benzyloxy)ethoxy)-...)
Affinity DataIC50: 23.4nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648285(US11884682, Compound 21 | 2-(3-methoxy-4-((5-(thio...)
Affinity DataIC50: 25.7nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648283(US11884682, Compound 19 | 2-(3-methoxy-4-((5-(thio...)
Affinity DataIC50: 28.8nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648287(US11884682, Compound 23 | 2-methoxy-4-((2-((5-meth...)
Affinity DataIC50: 31.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648303(US11884682, Compound 37 | 2-methoxy-4-morpholino-N...)
Affinity DataIC50: 36.3nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50095997(3',4',7-trihydroxyisoflavone | CHEMBL13486)
Affinity DataIC50: 38nMAssay Description:Inhibition of human MIF tautomerase activity expressed in Escherichia coli BL21 (DE3) using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50313986(3-(3,4-dihydroxyphenyl)-4H-chromen-4-one | CHEMBL1...)
Affinity DataIC50: 38nMAssay Description:Inhibition of MIFMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50095997(3',4',7-trihydroxyisoflavone | CHEMBL13486)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human His-tagged MIF tautomerization expressed in Escherichia coli BL21 (DE3) using D-dopachrome as substrate after 10 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648294(US11884682, Compound 28 | Trans-4-(3-methoxy-4-((5...)
Affinity DataIC50: 38nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648300(US11884682, Compound 34 | 2-methoxy-4-morpholino-N...)
Affinity DataIC50: 46.8nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648288(US11884682, Compound 24 | 2-methoxy-4-((1-((5-meth...)
Affinity DataIC50: 49nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50326574(6-phenylpyridazin-3-yl thiophene-2-carboxylate | C...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50326574(6-phenylpyridazin-3-yl thiophene-2-carboxylate | C...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648299(US11884682, Compound 33 | 4-(6-oxa-3-azabicyclo[3....)
Affinity DataIC50: 51.3nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648264(US11884682, Compound 6 | 2,4-dimethoxy-N-(5-(thiaz...)
Affinity DataIC50: 67.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM33627(cid_2202888 | butyl 1,3-benzoxazol-2-ylsulfanylmet...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648280(US11884682, Compound 16 | 4-hydroxy-2-methoxy-N-(5...)
Affinity DataIC50: 81.3nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50167982(CHEMBL3797982)
Affinity DataIC50: 110nMAssay Description:Inhibition of MIF (unknown origin) tautomerase activity using dopachrome as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50209085(3-fluoro-4-hydroxybenzaldehyde (4-methoxyphenyl)hy...)
Affinity DataIC50: 130nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM33627(cid_2202888 | butyl 1,3-benzoxazol-2-ylsulfanylmet...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648284(US11884682, Compound 20 | 4-(2-(dimethylamino)etho...)
Affinity DataIC50: 174nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648279(US11884682, Compound 15 | 4-(benzyloxy)-2-methoxy-...)
Affinity DataIC50: 200nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50209081(3-chloro-4-hydroxybenzaldehyde (4-methoxyphenyl)hy...)
Affinity DataIC50: 220nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50203072(Allylisothiocyanate | 3-isothiocyanatoprop-1-ene |...)
Affinity DataIC50: 250nMAssay Description:Inhibition of macrophage migration inhibitory factor tautomerase activity in human Jurkat T cells using L-dopachrome methyl ester as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648266(US11884682, Compound 8 | N-(5-(3-fluorothiophen-2-...)
Affinity DataIC50: 288nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50326573(1-Phenyl-3-(2-thiazolyl)-2-thiourea | 1-phenyl-3-(...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human MIF tautomerase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50209089(3-bromo-4-hydroxybenzaldehyde (4-methoxyphenyl)hyd...)
Affinity DataIC50: 330nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM92515(RDR 03785, 11)
Affinity DataIC50: 360nMAssay Description:Covalent inhibition of MIF (unknown origin) tautomerase activity using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50458547(CHEMBL4203719)
Affinity DataIC50: 370nMAssay Description:Inhibition of MIF (unknown origin) tautomerase activity using dopa as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50180758(4-((pyridin-4-ylthio)methyl)benzene-1,2-diol | CHE...)
Affinity DataIC50: 400nMAssay Description:Inhibition of MIFMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50167987(CHEMBL3799453)
Affinity DataIC50: 410nMAssay Description:Inhibition of MIF (unknown origin) tautomerase activity using dopachrome as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50326573(1-Phenyl-3-(2-thiazolyl)-2-thiourea | 1-phenyl-3-(...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human MIF tautomerase activity in presence of Triton X-100 as detergentMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50553880(CHEMBL4761710)
Affinity DataIC50: 470nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) using 4-HPP as substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM50209090(4-hydroxybenzaldehyde (4-methoxyphenyl)hydrazone |...)
Affinity DataIC50: 480nMAssay Description:Inhibition of MIF tautomerase activity by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Nanjing Immunophage Biotech Co.

US Patent
LigandPNGBDBM648304(US11884682, Compound 38 | 2,4-dimethoxy-N-((5-(thi...)
Affinity DataIC50: 490nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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