Compile Data Set for Download or QSAR
Report error Found 4403 of ic50 data for polymerid = 513,50004321,50007687
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629264(CHEMBL5426560)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629268(CHEMBL5421280)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629260(CHEMBL5407182)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629267(CHEMBL5406146)
Affinity DataIC50: 0.0230nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629258(CHEMBL5414576)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629277(CHEMBL5398425)
Affinity DataIC50: 0.0360nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629266(CHEMBL5437264)
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629263(CHEMBL5428430)
Affinity DataIC50: 0.0540nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50170284(GSK2141795 | GSK2141795C | Uprosertib)
Affinity DataIC50: 0.0660nMAssay Description:Inhibition of AKT1 (unknown origin) using Sox-AKT-tide as substrate by continuous real time fluorescence detection based [gamma33P]ATP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50502477(ASB183 | ASB-183 | Afuresertib | GSK-2110183C | GS...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of AKT1 (unknown origin) using Sox-AKT-tide as substrate by continuous real time fluorescence detection based [gamma33P]ATP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629272(CHEMBL5400934)
Affinity DataIC50: 0.0830nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629262(CHEMBL5408482)
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM182489(US9145392, 190)
Affinity DataIC50: 0.100nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629271(CHEMBL5438374)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629280(CHEMBL5399312)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM182480(US9145392, 181)
Affinity DataIC50: 0.150nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM15131(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50298443(5-(5-((S)-2-amino-3-(1H-indol-3-yl)propoxy)pyridin...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM431867(US10550114, Compound 1a)
Affinity DataIC50: 0.200nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM431867(US10550114, Compound 1a)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of 6xHis-tagged full-length wild-type AKT1 (unknown origin) expressed in baculovirus infected Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629274(CHEMBL5411877)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM182699(US9145392, 400)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430058(US10538528, Compound 2)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430029(US10538528, Compound 5)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430060(US10538528, Compound 7)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430061(US10538528, Compound 8)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430062(US10538528, Compound 9)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430063(US10538528, Compound 10)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430030(US10538528, Compound 11)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430064(US10538528, Compound 12)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430070(US10538528, Compound 28)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430051(US10538528, Compound 37)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430066(US10538528, Compound 38)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430052(US10538528, Compound 39)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430053(US10538528, Compound 40)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430054(US10538528, Compound 41)
Affinity DataIC50: 0.300nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50629275(CHEMBL5405650)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM9048(US8536193, 10-5)
Affinity DataIC50: 0.340nMAssay Description:Activated Akt isoforms and pleckstrin homology domain deletion constructs were assayed utilizing a GSK-derived biotinylated peptide substrate. The e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM16532(pyrazolopyridine analog, 9g | (2S)-1-(1H-indol-3-y...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.350nMAssay Description:Envision model plate reader (Molecular Devices)White 384-well plate (Thermo, Art. No. #264706)Main reagents included in an HTRF kinEASE TK kit (Cisbi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.350nMAssay Description:After all the reagents were prepared according to the above method, except for the enzyme, the reagents were equilibrated to the room temperature and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.350nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM102310(US8536193, 10-4)
Affinity DataIC50: 0.380nMpH: 7.5Assay Description:Activated Akt isoforms and pleckstrin homology domain deletion constructs were assayed utilizing a GSK-derived biotinylated peptide substrate. The e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM182551(US9145392, 252)
Affinity DataIC50: 0.400nMpH: 7.5Assay Description:A TTP Mosquito liquid handling instrument is used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM187363(US9169243, 11 | US9908875, 11)
Affinity DataIC50: 0.400nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection. This is a competitive, time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM431867(US10550114, Compound 1a)
Affinity DataIC50: 0.400nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430028(US10538528, Compound 1)
Affinity DataIC50: 0.400nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430067(US10538528, Compound 3)
Affinity DataIC50: 0.400nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430068(US10538528, Compound 4)
Affinity DataIC50: 0.400nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM430059(US10538528, Compound 6)
Affinity DataIC50: 0.400nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Displayed 1 to 50 (of 4403 total ) | Next | Last >>
Jump to: