Compile Data Set for Download or QSAR
Report error Found 20 of ic50 data for polymerid = 5076,50004528,50004742
LigandPNGBDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 210nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 720nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50135169((2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50236531((2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM87064(Sulfonamide derivative, 5)
Affinity DataKi:  4.20E+3nM IC50: 2.53E+3nMAssay Description:The enzyme activities in the absence of drugs or chemicals were taken as 100%. For each drug or chemical, an activity%-(drug) graph was drawn and dr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Target6-phosphogluconate dehydrogenase, decarboxylating(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50342610((2R,3R,4S)-2,3,4-trihydroxy-5-(hydroxyamino)-5-oxo...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenaseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM94597((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...)
Affinity DataKi:  8.30E+3nM IC50: 8.40E+3nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataKi:  1.01E+4nM IC50: 1.20E+4nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataKi:  5.09E+4nM IC50: 5.50E+4nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM87063(Sulfonamide derivative, 3)
Affinity DataKi:  8.78E+4nM IC50: 6.01E+4nMAssay Description:The enzyme activities in the absence of drugs or chemicals were taken as 100%. For each drug or chemical, an activity%-(drug) graph was drawn and dr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataKi:  1.27E+5nM IC50: 1.25E+5nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  1.37E+5nM IC50: 1.42E+5nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50187665((-)-epigallocatechin | CHEMBL47386)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50373220((-)-GALLOCATECHIN)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM23417(cid_72276 | (-)-Epicatechin | (2R,3R)-2-(3,4-dihyd...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM233150(Gadopentetic acid)
Affinity DataKi:  7.34E+7nM IC50: 2.09E+8nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM97162(MLS002153782 | RITODRINE | cid_31728 | SMR00123316...)
Affinity DataKi:  6.04E+6nM IC50: 3.66E+6nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  2.11E+6nM IC50: 3.27E+6nMAssay Description:In order to determine the effects of some drugs on human 6PGD, concentrations of ketotifen (0.0018-0.0282 mM), dacarbazine (0.0049-0.054 mM), meloxic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50043906(CHEMBL269001 | Dorzolamide | MK-507 | US10172837, ...)
Affinity DataKi:  3.14E+6nM IC50: 1.41E+6nMAssay Description:The enzyme activities in the absence of drugs or chemicals were taken as 100%. For each drug or chemical, an activity%-(drug) graph was drawn and dr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed