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TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50583309(CHEMBL4204851)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50096484((4S,6R)-6-Allyl-4-(naphthalene-2-sulfonyl)-5-oxo-h...)
Affinity DataIC50: 0.0360nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50066997(CHEMBL2367632 | (3aS,6R)-6-Allyl-4-methanesulfonyl...)
Affinity DataIC50: 0.0470nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120437(CHEMBL3617973)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120437(CHEMBL3617973)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate measured after 60 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120437(CHEMBL3617973)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50058495(3-{2-[2-(Thiophene-2-carbonylsulfanyl)-propionylam...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120428(CHEMBL3617966)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50556037(CHEMBL4744163)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate measured after 60 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50608626(CHEMBL5280380)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104820(US8569314, 5)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104821(US8569314, 9)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104822(US8569314, 23)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104823(US8569314, 35)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104824(US8569314, 50)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104825(US8569314, 53)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM104826(US8569314, 56)
Affinity DataIC50: 0.300nMAssay Description:In vitro HNE inhibition assay. The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amido...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189812(US9174997, 10)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189813(US9174997, 12)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189814(US9174997, 14)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189815(US9174997, 18)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189818(US9174997, 27)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189819(US9174997, 32)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189820(US9174997, 33)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189821(US9174997, 36)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189822(US9174997, 41)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189823(US9174997, 43 (Diastereomer 1))
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189831(US9174997, 51)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189835(US9174997, 55)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189860(US9174997, 80)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189865(US9174997, 85)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189871(US9174997, 91)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189876(US9174997, 96)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189883(US9174997, 103)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189896(US9174997, 116)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189900(US9174997, 120)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189908(US9174997, 128)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189921(US9174997, 141)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189924(US9174997, 144)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM211514(US9290457, Example 1.56)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120436(CHEMBL3617972)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189817(US9174997, 22)
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50066999((S)-3,3-Diethyl-2-[4-(4-methyl-piperazine-1-carbon...)
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189811(US9174997, 6)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120429(CHEMBL3617965)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50096486(benzyl (3aS,6aR)-4-acetyl-6-allyl-5-oxohexahydropy...)
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50612149(CHEMBL5284383)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of elastase in human neutrophil using MeOSuc-AAPV-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50429202(LYNGBYASTATIN 7)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of elastase in human neutrophil using MeOSuc-AAPV-AMC as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM189849(US9174997, 69)
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetNeutrophil elastase(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50120424(CHEMBL3617970)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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