Compile Data Set for Download or QSAR
Report error Found 31 of ic50 data for polymerid = 50007220
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50552053(Glaucocalyxin A)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in CRP-induced platelet-aggregation preincubated for 10 mins followed by collagen ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50552053(Glaucocalyxin A)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in collagen-induced platelet-aggregation preincubated for 10 mins followed by coll...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)
Affinity DataIC50: 31nMAssay Description:Modulation of GP6 in human platelets assessed as reduction in convulxin-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)
Affinity DataIC50: 48nMAssay Description:Modulation of GP6 in human platelets assessed as reduction in convulxin-induced P-selectin expression preincubated for 20 mins followed by convulxin ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 120nMAssay Description:Inhibition of GP6 in human whole blood assessed as protein-mediated platelet aggregation preincubated for 15 mins followed by collagen stimulation an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM250082(US9447106, 27b (peak 2) | US9556188, Compound 27a)
Affinity DataIC50: 510nMAssay Description:Inhibition of GP6 in human whole blood assessed as protein-mediated platelet aggregation preincubated for 15 mins followed by collagen stimulation an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)
Affinity DataIC50: 570nMAssay Description:Modulation of GP6 in human platelets reduction in collagen-induced platelet aggregation preincubated for 20 mins followed by collagen stimulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM194087(US9199997, 9 | US9879013, 19(2) | US20230364079, E...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GP6 in human whole blood assessed as protein-mediated platelet aggregation preincubated for 15 mins followed by collagen stimulation an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50175583(ACP-196 | Acalabrutinib | US9758524, Example 6 | U...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of GP6 in human whole blood assessed as protein-mediated platelet aggregation preincubated for 15 mins followed by collagen stimulation an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in CRP-induced platelet-aggregation preincubated for 60 secs followed by collagen ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in collagen-induced platelet-aggregation preincubated for 60 secs followed by coll...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211284(CHEMBL3959435)
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM291522(US9580449, Example A39 | 1-(4-(((6-amino-5-(4-phen...)
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of GP6 in human whole blood assessed as protein-mediated platelet aggregation preincubated for 15 mins followed by collagen stimulation an...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211284(CHEMBL3959435)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211282(CHEMBL308493)
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211280(S007-1558 (S))
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 1.04E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211282(CHEMBL308493)
Affinity DataIC50: 1.61E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211280(S007-1558 (S))
Affinity DataIC50: 2.53E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in CRP-induced platelet-aggregation preincubated for 60 secs followed by collagen ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-induced platelet aggregation preincubated for 60 sec ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in collagen-induced platelet-aggregation preincubated for 60 secs followed by coll...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50016900(CINANSERIN | CHEMBL18786 | N-(2-(3-(dimethylamino)...)
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 60...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211282(CHEMBL308493)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211284(CHEMBL3959435)
Affinity DataIC50: 5.35E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211283(CHEMBL2263356)
Affinity DataIC50: 8.68E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CVX-induced platelet aggregation preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211283(CHEMBL2263356)
Affinity DataIC50: 1.26E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 1.58E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211280(S007-1558 (S))
Affinity DataIC50: 1.81E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet glycoprotein VI(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50211283(CHEMBL2263356)
Affinity DataIC50: 5.00E+5nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-XL-induced platelet aggregation preincubated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed