Compile Data Set for Download or QSAR
Report error Found 136 of ic50 data for polymerid = 50006244,50006988
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606909(CHEMBL5219888)
Affinity DataIC50: 112nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606907(CHEMBL5220224)
Affinity DataIC50: 134nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587578(CHEMBL5091825)
Affinity DataIC50: 144nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587578(CHEMBL5091825)
Affinity DataIC50: 144nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528763(CHEMBL4472697)
Affinity DataIC50: 280nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562506(CHEMBL4791168)
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal 6His-tagged recombinant human IDO2 (15 to 420 residues) expressed in Escherichia coli using L-Trp as substrate by UV absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562506(CHEMBL4791168)
Affinity DataIC50: 310nMAssay Description:Inhibition of IDO2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587572(CHEMBL5085580)
Affinity DataIC50: 362nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606906(CHEMBL5221035)
Affinity DataIC50: 387nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50442991(GNF-Pf-3777 | CHEMBL432537 | US10669273, Compound ...)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528779(CHEMBL4514196)
Affinity DataIC50: 490nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606908(CHEMBL5221037)
Affinity DataIC50: 575nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528780(CHEMBL4436582)
Affinity DataIC50: 590nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 630nMAssay Description:Inhibition of IDO2 (unknown origin) using D-Trp as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587576(CHEMBL5082481)
Affinity DataIC50: 689nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 710nMAssay Description:Inhibition of N-terminal His-tagged human IDO2 expressed in Escherichia coli expression systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587574(CHEMBL5090441)
Affinity DataIC50: 726nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587566(CHEMBL5092513)
Affinity DataIC50: 794nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587567(CHEMBL5091241)
Affinity DataIC50: 830nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587577(CHEMBL5091415)
Affinity DataIC50: 865nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587579(CHEMBL5091243)
Affinity DataIC50: 930nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587573(CHEMBL5091590)
Affinity DataIC50: 947nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587570(CHEMBL5093816)
Affinity DataIC50: 958nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587575(CHEMBL5084150)
Affinity DataIC50: 958nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387356(US10294212, No. 2 | N3-(3-Chloro- 4-fluorophenyl) ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human indoleamine 2,3-dioxygenase-2 (hIDO2) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM387592(US10294212, No. 184 | N3-(3,4- difluoro- phenyl)-7...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human indoleamine 2,3-dioxygenase-2 (hIDO2) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587571(CHEMBL5078912)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587580(CHEMBL5088729)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587569(CHEMBL5078101)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM48009(SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50442991(GNF-Pf-3777 | CHEMBL432537 | US10669273, Compound ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50402289(TENATOPRAZOLE)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402289(TENATOPRAZOLE)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IDO2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50442991(GNF-Pf-3777 | CHEMBL432537 | US10669273, Compound ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IDO2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587568(CHEMBL5084767)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50442987(8-Bromotryptanthrin | CHEMBL72165)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50514040(CHEMBL4436480)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human IDO2 transfected in human U87MG cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50514041(CHEMBL4452150)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of human IDO2 transfected in human U87MG cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | Indolo[2,1-b]quinazoline-6,12-dione...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM48009(SMR000544298 | 8-fluoranylindolo[2,1-b]quinazoline...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50507277(CHEMBL4578334)
Affinity DataIC50: 7.68E+3nMAssay Description:Inhibition of mouse IDO2 expressed in human T-REx cells using L-tryptophan as substrate after 20 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50514038(CHEMBL4577825)
Affinity DataIC50: 8.05E+3nMAssay Description:Inhibition of human IDO2 transfected in human U87MG cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50442988(CHEMBL3087009)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Mouse)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM47032(cid_3883 | 2-[[3-methyl-4-(2,2,2-trifluoroethoxy)p...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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