Report error Found 892 of ic50 data for polymerid = 50006042
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells assessed as reduction in MDP-induced IL8 production measured after 22 hrs by HTRF fluorescence ass...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of NOD2 in human monocytes assessed as reduction in MDP-induced TNFalpha production preincubated for 30 mins followed by MDP-stimulation a...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 129nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 233nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 243nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 323nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 352nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human NOD2 expressed in HEK-Blue cells assessed as inhibition of MDP-stimulated cell activation preincubated for 3 hrs followe...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human NOD2 in HEK-Blue hNOD2 cells assessed as secreted alkaline phosphatase reporter activity preincubated for 3 hrs followed...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as inhibition of MDP-induced NFkappaB activation-mediated SEAP release preincubated for ...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston
Curated by ChEMBL
University of Houston
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
