Compile Data Set for Download or QSAR
Report error Found 38 of ic50 data for polymerid = 50004332
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533247(CHEMBL4470356)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533247(CHEMBL4470356)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533251(CHEMBL4579540)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533251(CHEMBL4579540)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533246(CHEMBL4549646)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533246(CHEMBL4549646)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533249(CHEMBL4468555)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533249(CHEMBL4468555)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533248(CHEMBL4515745)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533248(CHEMBL4515745)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533245(CHEMBL4579162)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533245(CHEMBL4579162)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533244(CHEMBL4466617)
Affinity DataIC50: 19nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533244(CHEMBL4466617)
Affinity DataIC50: 19nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533250(CHEMBL4483703)
Affinity DataIC50: 24nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50533250(CHEMBL4483703)
Affinity DataIC50: 24nMAssay Description:Inhibition of human CENP-E motor domain assessed as ADP levels preincubated with protein motor domain/microtubule for 60 mins followed by ATP additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438555(CHEMBL2413142)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438554(CHEMBL2413143)
Affinity DataIC50: 35nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438549(CHEMBL2413146)
Affinity DataIC50: 50nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438562(CHEMBL2413135)
Affinity DataIC50: 72nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438560(CHEMBL2413137)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438553(CHEMBL2413144)
Affinity DataIC50: 140nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438561(CHEMBL2413136)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438556(CHEMBL2413141)
Affinity DataIC50: 370nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438552(CHEMBL2413145)
Affinity DataIC50: 540nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438550(CHEMBL2413133)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ATPase activity of CENP-E motor domain (unknown origin) by high throughput screening assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438550(CHEMBL2413133)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438563(CHEMBL2413134)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438557(CHEMBL2413140)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438558(CHEMBL2413139)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438551(CHEMBL2413132)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of ATPase activity of CENP-E motor domain (unknown origin) by high throughput screening assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50438559(CHEMBL2413138)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human ATPase activity of CENP-E motor domain assessed as ADP production after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056904(cid_65751 | 3,8-Dihydroxy-11-oxo-1-(2-oxo-heptyl)-...)
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of basal ATPase activity of human CENP-E by pyruvate kinase/lactate dehydrogenase-linked assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50252149((S)-4-(2,5-difluorophenyl)-N-((3R,4S)-3-fluoro-1-m...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of cloned human CENP-EMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50404035(CHEMBL5287177)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50056904(cid_65751 | 3,8-Dihydroxy-11-oxo-1-(2-oxo-heptyl)-...)
Affinity DataIC50: 9.14E+4nMAssay Description:Inhibition of microtubule-stimulated ATPase activity of human CENP-E by pyruvate kinase/lactate dehydrogenase-linked assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50403553(CHEMBL5266739)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCentromere-associated protein E(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50403554(CHEMBL5282512)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails
PubMed