Compile Data Set for Download or QSAR
Report error Found 26 of ic50 data for polymerid = 50003986
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543400(CHEMBL4640248)
Affinity DataIC50: 34nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543404(CHEMBL4640154)
Affinity DataIC50: 75nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543405(CHEMBL4639417)
Affinity DataIC50: 120nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50247677((3S,8S)-14,16-dihydroxy-3,8-dimethyl-3,4,5,6,9,10-...)
Affinity DataIC50: 210nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543397(CHEMBL4646593)
Affinity DataIC50: 250nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543399(CHEMBL4648793)
Affinity DataIC50: 270nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543402(CHEMBL4634960)
Affinity DataIC50: 370nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 400nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50543401(CHEMBL4644092)
Affinity DataIC50: 440nMAssay Description:Inhibition of CBR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataIC50: 670nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308752(3-(1-tert-butyl-4-amino-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50: 759nMAssay Description:Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiolMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308752(3-(1-tert-butyl-4-amino-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50: 788nMAssay Description:Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiolMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241828(CHEMBL4089817)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human CBR1 using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308753(3-(Methyl-N-ethylcarbamate)-5-hydroxybenz[f]indazo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50073099(cid_16196977 | (9Z,11E)-(4R,6R,8R)-17,19-Dihydroxy...)
Affinity DataIC50: 3.27E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataIC50: 3.78E+3nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308751(3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308750(3-(Methyl-N-ethylcarbamate)-6-(N0-methylphenylamin...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241817(CHEMBL4081954)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant human CBR1 using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308754(3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308750(3-(Methyl-N-ethylcarbamate)-6-(N0-methylphenylamin...)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50: 1.27E+4nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308751(3-(methyl-N-ethylcarbamate)-6-(N0-ethylphenylamino...)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308753(3-(Methyl-N-ethylcarbamate)-5-hydroxybenz[f]indazo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23419(CHEMBL9352 | (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl...)
Affinity DataIC50: 2.15E+4nMAssay Description:Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonyl reductase [NADPH] 1(Human)
Gifu Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308754(3-(Methyl-N-ethylcarbamate)-6,7-dichloro-5,8-dimet...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed