Compile Data Set for Download or QSAR
Report error Found 12 of ic50 data for polymerid = 50003834,50006979
TargetDNA polymerase iota(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(CHEMBL1014 | TCV-116 | candesartancilexetil | Atac...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human DNA polymerase iota preincubated for 15 mins followed by replicating non-damaged DNA substrate addition measured after 30 mins in...More data for this Ligand-Target Pair
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PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50276865(4-[(2E)-but-2-enoyl]-2-[(1E,3E)-5-hydroxyhexa-1,3-...)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of mouse DNA polymerase iotaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50276936(4-(3-hydroxybutanoyl)-2-[(1E,3E)-5-hydroxyhexa-1,3...)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of mouse DNA polymerase iotaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50104668(CHEMBL3593571)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of C-terminal His6-tagged recombinant mouse DNA polymerase iota using poly(dA)/oligo(dT)18 and [3H]dTTP as template-primer and nucleotide ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 6.38E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Mouse)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA polymerase iota(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50428818(CHEMBL3142662)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed