Compile Data Set for Download or QSAR
Report error Found 140 of ic50 data for polymerid = 50003614,50003837
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50: 0.960nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50417462(CHEMBL469696)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443406(CHEMBL3086823)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443409(CHEMBL3086836)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443400(CHEMBL3086821)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443408(CHEMBL3086837)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443405(CHEMBL3086824)
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443404(CHEMBL3086825)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443392(CHEMBL1472563)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322836(rac-N-(3-methyl-1-(piperidin-1-yl)pentan-3-yl)-N-(...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443399(CHEMBL3086822)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443398(CHEMBL1514777)
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443407(CHEMBL3086838)
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443394(CHEMBL3086834)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443392(CHEMBL1472563)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322837(rac-N-(1-(4-fluoropiperidin-1-yl)-3-methylpentan-3...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443393(CHEMBL1553073)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443395(CHEMBL1315807)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443396(CHEMBL3086833)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322842(N-((1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50417464(CHEMBL1289677)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322838(rac-N-(1-(4,4-difluoropiperidin-1-yl)-3-methylpent...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322839(rac-N-(3-methyl-1-morpholinopentan-3-yl)-N-((1-met...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443403(CHEMBL3086826)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50417462(CHEMBL469696)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443417(CHEMBL3086828)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50322834(N-((1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50417463(CHEMBL1289571)
Affinity DataIC50: 31.6nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443396(CHEMBL3086833)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50348617(CHEMBL1801361)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50348617(CHEMBL1801361)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443402(CHEMBL3086827)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50348615(CHEMBL1801359)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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