Compile Data Set for Download or QSAR
Report error Found 235 of ic50 data for polymerid = 50002716
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038646(2-(6-(4-tert-butylphenyl)-2,2-dimethyl-7-phenyl-2,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038649(ML-3000 | [2-(4-Chloro-phenyl)-6,6-dimethyl-1-phen...)
Affinity DataIC50: 180nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038647([2-(4-Methoxy-phenyl)-6,6-dimethyl-1-phenyl-6,7-di...)
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043360(1,8-Dihydroxy-10-(4-phenyl-butyryl)-10H-anthracen-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043362(1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acet...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043353(1,8-Dihydroxy-10-(3,4,5-trihydroxy-benzylidene)-10...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059631(6-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 400nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50004677(Acetic acid 4-acetoxy-6-chloro-2,3-dimethoxy-napht...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043352(10-(3,4-dihydroxybenzylidene)-1,8-dihydroxyanthrac...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50004677(Acetic acid 4-acetoxy-6-chloro-2,3-dimethoxy-napht...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043357(1,8-Dihydroxy-10-(3-phenyl-propionyl)-10H-anthrace...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043371(1,8-Dihydroxy-10-[2-(4-methoxy-phenyl)-acetyl]-10H...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059608(5-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 500nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50387594(CHEMBL2057741)
Affinity DataIC50: 510nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotriene B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50041799(1,8-Dihydroxy-2-[3-(3,4,5-trihydroxy-phenyl)-propy...)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043355(10-[2-(4-Benzyloxy-phenyl)-acetyl]-1,8-dihydroxy-1...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059604(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 600nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059616(3-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 600nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059599(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 700nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038649(ML-3000 | [2-(4-Chloro-phenyl)-6,6-dimethyl-1-phen...)
Affinity DataIC50: 760nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotriene B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50041780(2-(2,5-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50387596(CHEMBL2057740)
Affinity DataIC50: 970nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotriene B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043373(10-[2-(3,4-Dihydroxy-phenyl)-acetyl]-1,8-dihydroxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50041782(3-(2,5-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043363(1,8-Dihydroxy-10-[3-(4-hydroxy-phenyl)-propionyl]-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043368(1,8-Dihydroxy-10-[3-(4-methoxy-phenyl)-propionyl]-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059627(2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50059634(2-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:5-LO inhibitory activity, measured by production of 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4) in bovine polymorphonuclear leu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038653([6,6-Dimethyl-2-(4-nitro-phenyl)-1-phenyl-6,7-dihy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038645([6,6-Dimethyl-2-(4-phenoxy-phenyl)-1-phenyl-6,7-di...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038654(2-(6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrr...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038657([2-(3-Chloro-phenyl)-6,6-dimethyl-1-phenyl-6,7-dih...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038655([2-(3,4-Dichloro-phenyl)-6,6-dimethyl-1-phenyl-6,7...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038656([6,6-Dimethyl-1-phenyl-2-(2,3,4-trichloro-phenyl)-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043357(1,8-Dihydroxy-10-(3-phenyl-propionyl)-10H-anthrace...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043352(10-(3,4-dihydroxybenzylidene)-1,8-dihydroxyanthrac...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043348(1,8-dihydroxy-10-(4-nitrobenzylidene)anthracen-9(1...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043362(1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acet...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043354(1,8-Dihydroxy-10-phenylacetyl-10H-anthracen-9-one ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043347(1,8-Dihydroxy-10-(3-phenyl-propylidene)-10H-anthra...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50041774(1,8-Dihydroxy-2-[3-(4-hydroxy-phenyl)-propyl]-10H-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50041803(4-(1,8-Dihydroxy-9-oxo-9,10-dihydro-anthracen-2-yl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50041806(3-(3,4-Dihydroxy-benzyl)-1,8-dihydroxy-10H-anthrac...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in bovine polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043353(1,8-Dihydroxy-10-(3,4,5-trihydroxy-benzylidene)-10...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043356(1,8-Dihydroxy-10-[2-(4-nitro-phenyl)-acetyl]-10H-a...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043359(1,8-Dihydroxy-10-[2-(4-hydroxy-phenyl)-acetyl]-10H...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043364(1,8-Dihydroxy-10-(5-phenyl-pentanoyl)-10H-anthrace...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-lipoxygenase(Bovine)
Merckle

Curated by ChEMBL
LigandPNGBDBM50043366(10-[3-(4-Benzyloxy-phenyl)-propionyl]-1,8-dihydrox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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