Compile Data Set for Download or QSAR
Report error Found 945 of ic50 data for polymerid = 50002247,50006473
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(telomestatin | CHEMBL443683)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(telomestatin | CHEMBL443683)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human Telomerase activity in cell free system by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(telomestatin | CHEMBL443683)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50: 13nMAssay Description:Inhibition of telomerase activity in human MCF7 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50: 13nMAssay Description:Inhibition of telomerase activity in human H125 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50: 13nMAssay Description:Inhibition of telomerase activity in human HT-29 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50198341(CHEMBL3948172)
Affinity DataIC50: 13nMAssay Description:Inhibition of telomerase activity in human M14 cells using biotin-labeled TeloTAGGG as primer preincubated for 48 hrs followed by primer addition mea...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134027(N-[9-(2-Dimethylamino-ethylamino)-6-(3-pyrrolidin-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50310892(N,N'-(9-(2-(1-methylpyrrolidin-2-yl)ethylamino)acr...)
Affinity DataIC50: 18nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50310892(N,N'-(9-(2-(1-methylpyrrolidin-2-yl)ethylamino)acr...)
Affinity DataIC50: 18nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134010(N-[9-(2-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 20nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50440391(CHEMBL2425367)
Affinity DataIC50: 28nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50196500(trimethyl(2-{6,8,17,19-tetraoxo-18-[2-(trimethylaz...)
Affinity DataIC50: 30nMAssay Description:Inhibition of telomerase in JR8 cell extract by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134022(N,N'-(9-(4-acetylphenylamino)acridine-3,6-diyl)bis...)
Affinity DataIC50: 40nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50487893(CHEMBL2260109)
Affinity DataIC50: 41nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50487893(CHEMBL2260109)
Affinity DataIC50: 41nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134030(N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489002(CHEMBL2298058)
Affinity DataIC50: 49nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489002(CHEMBL2298058)
Affinity DataIC50: 49nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50058033(CHEMBL3330787)
Affinity DataIC50: 50nMAssay Description:Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134002(N-[9-(2-Piperidin-1-yl-ethylamino)-6-(3-pyrrolidin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134032(N,N'-(9-(cyclopropylamino)acridine-3,6-diyl)bis(3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489008(CHEMBL2298055)
Affinity DataIC50: 51nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50489008(CHEMBL2298055)
Affinity DataIC50: 51nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 52nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50488996(CHEMBL2298050)
Affinity DataIC50: 56nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50488996(CHEMBL2298050)
Affinity DataIC50: 56nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50339190(telomestatin | CHEMBL443683)
Affinity DataIC50: 58nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50196492(2,9-bis-[2-(2-hydroxy-ethylamino)-ethyl]-anthra[2,...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in JR8 cell extract by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134009(N,N'-(9-(3-(dimethylamino)propylamino)acridine-3,6...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134019(N,N'-(9-(3-aminophenylamino)acridine-3,6-diyl)bis(...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50107609(CHEMBL2170855 | CHEMBL337559 | TMPyP4 | 5,10,15,20...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134018(N-[9-(4-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376748(CHEMBL259739 | Phen-DC3)
Affinity DataIC50: 63nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134030(N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50058035(CHEMBL3330789)
Affinity DataIC50: 70nMAssay Description:Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134025(N-[9-(4-Fluoro-phenylamino)-6-(3-pyrrolidin-1-yl-p...)
Affinity DataIC50: 70nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134018(N-[9-(4-Amino-phenylamino)-6-(3-pyrrolidin-1-yl-pr...)
Affinity DataIC50: 74nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50058037(CHEMBL3330791)
Affinity DataIC50: 80nMAssay Description:Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50150618(N1-(4-(3,6-bis(3-(pyrrolidin-1-yl)propanamido)acri...)
Affinity DataIC50: 80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134023(N,N'-(9-(4-aminophenylamino)acridine-2,6-diyl)bis(...)
Affinity DataIC50: 80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134008(N-[9-(3-Dimethylamino-propylamino)-6-(3-pyrrolidin...)
Affinity DataIC50: 80nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134030(N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human telomerase in A549 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50134000(N,N'-(9-(cyclohexylamino)acridine-3,6-diyl)bis(3-(...)
Affinity DataIC50: 90nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50: 93nMAssay Description:Inhibition of human telomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50: 93nMAssay Description:Inhibition of telomerase in human HeLa cells after 2 hrs by [alpha-32P]dGTP incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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