Compile Data Set for Download or QSAR
Report error Found 82 of ic50 data for polymerid = 50001579,50004130
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EphB2 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHB2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM378887(US10266537, Compound 31)
Affinity DataIC50: 10nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHB2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50331095(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant EphB2 (unknown origin) by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50086441(CHEMBL3426225 | US10266537, Compound 3)
Affinity DataIC50: 26nMAssay Description:Inhibition of human EphB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50086441(CHEMBL3426225 | US10266537, Compound 3)
Affinity DataIC50: 26nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50331095(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant EphB2 (unknown origin) by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM378885(US10266537, Compound 93)
Affinity DataIC50: 33nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHB2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 42.4nMAssay Description:Inhibition of human EPHB2 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50538442(CHEMBL4638981)
Affinity DataIC50: 71nMAssay Description:Inhibition of EPHB2 (unknown origin) assessed as residual activity incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50328755(2-(3-(3-tert-butyl-5-(3-(2,3-dichlorophenyl)ureido...)
Affinity DataIC50: 82nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50538438(CHEMBL4640297)
Affinity DataIC50: 93nMAssay Description:Inhibition of EPHB2 (unknown origin) assessed as residual activity incubated for 5 mins in presence of [gamma-33ATP] by scintillation counting based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 115nMAssay Description:Inhibition of human EPHB2 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 160nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 199nMAssay Description:Inhibition of EPHB2 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498455(CHEMBL3596879)
Affinity DataIC50: 880nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50462709(CHEMBL4245507)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EPH-B2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50563891(CHEMBL4793380)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant human EphB2 (560 to end residues) using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins in presence of [gamma-33ATP] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM4622(CHEMBL127907 | 3-[(6,7-dimethoxyquinazolin-4-yl)am...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of EphB2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498458(CHEMBL3596868)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498452(CHEMBL3596873)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498453(CHEMBL3596862)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498449(CHEMBL3596889)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of human recombinant GST-tagged EPHB2 cytoplasmic domain (616 to 884 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498457(CHEMBL3596893)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50498459(CHEMBL3596892)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHB2 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428059(CHEMBL2322989)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of ephrin-B1-Fc from EphB2 receptor Fc ectodomain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM39299(N-[3-(1-imidazolyl)propyl]-7H-purin-6-amine | SMR0...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM4621(N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazoli...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50321943(N-(4-Aminosulfonylphenyl)-2-morpholino-9H-purin-6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition EphB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50041978(CHEMBL3134157)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50605384(CHEMBL5175977)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50401152(CHEMBL2205766)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EPHB2 using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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