Compile Data Set for Download or QSAR
Report error Found 27 of ic50 data for polymerid = 50001531
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18128(CHEMBL310012 | (2S)-2-[(2S)-2-amino-3-(4-hydroxyph...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097749([2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50091497((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50091497((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18128(CHEMBL310012 | (2S)-2-[(2S)-2-amino-3-(4-hydroxyph...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097746((S)-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104311((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097748([2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18132((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50091496((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097744((S)-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097744((S)-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104310((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 124nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097747([2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104313((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 245nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097745([2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081838([(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 510nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081839([(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 800nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081834((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 900nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081837([(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104314((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104312((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081841([(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081840((S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50: 3.80E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081836([(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-...)
Affinity DataIC50: 7.80E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081835((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18128(CHEMBL310012 | (2S)-2-[(2S)-2-amino-3-(4-hydroxyph...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed