Compile Data Set for Download or QSAR
Report error Found 36 of ic50 data for polymerid = 50001398,50001921,50006609
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110309(Methyl-(3-piperidin-1-yl-propyl)-quinolin-4-yl-ami...)
Affinity DataIC50: 16nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110306((6-Piperidin-1-yl-hexyl)-(1,2,3,4-tetrahydro-acrid...)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110285({3-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-propyl}-q...)
Affinity DataIC50: 31nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110303((2-Piperidin-1-yl-ethyl)-(1,2,3,4-tetrahydro-acrid...)
Affinity DataIC50: 34nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110286((3-Piperidin-1-yl-propyl)-(1,2,3,4-tetrahydro-acri...)
Affinity DataIC50: 45nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110300(N-(4-(3-(piperidin-1-yl)propoxy)phenethyl)-5,6,7,8...)
Affinity DataIC50: 48nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110296({4-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-butyl}-(1...)
Affinity DataIC50: 48nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110298(Ethyl-(3-piperidin-1-yl-propyl)-quinolin-4-yl-amin...)
Affinity DataIC50: 49nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110288([4-(3-Piperidin-1-yl-propoxy)-phenyl]-quinolin-4-y...)
Affinity DataIC50: 51nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110294((5-Piperidin-1-yl-pentyl)-quinolin-4-yl-amine; Oxa...)
Affinity DataIC50: 53nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110287((3-Piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxa...)
Affinity DataIC50: 64nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110284((4-Piperidin-1-yl-butyl)-quinolin-4-yl-amine; Oxal...)
Affinity DataIC50: 64nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110290({4-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-butyl}-qu...)
Affinity DataIC50: 73nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110297((6-Piperidin-1-yl-hexyl)-quinolin-4-yl-amine; Oxal...)
Affinity DataIC50: 84nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110299({3-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-propyl}-(...)
Affinity DataIC50: 95nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110302(Acridin-9-yl-(3-piperidin-1-yl-propyl)-amine; Oxal...)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110311({2-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-ethyl}-qu...)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110282((7-Chloro-quinolin-4-yl)-(7-piperidin-1-yl-heptyl)...)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110293(Methyl-(2-piperidin-1-yl-ethyl)-quinolin-4-yl-amin...)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110304((7-Chloro-quinolin-4-yl)-(5-piperidin-1-yl-pentyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110283((7-Chloro-quinolin-4-yl)-(4-piperidin-1-yl-butyl)-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110295((7-Chloro-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110305((7-Chloro-quinolin-4-yl)-(3-piperidin-1-yl-propyl)...)
Affinity DataIC50: 200nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110313((2-Piperidin-1-yl-ethyl)-quinolin-4-yl-amine; Oxal...)
Affinity DataIC50: 210nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110289((7-Chloro-quinolin-4-yl)-(10-piperidin-1-yl-decyl)...)
Affinity DataIC50: 220nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110301((7-Chloro-quinolin-4-yl)-(12-piperidin-1-yl-dodecy...)
Affinity DataIC50: 230nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110312((7-Chloro-quinolin-4-yl)-(8-piperidin-1-yl-octyl)-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110291((7-Chloro-quinolin-4-yl)-[4-(3-piperidin-1-yl-prop...)
Affinity DataIC50: 310nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110310((3-Methyl-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...)
Affinity DataIC50: 340nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110281(Methyl-(3-piperidin-1-yl-propyl)-(1,2,3,4-tetrahyd...)
Affinity DataIC50: 360nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110308((7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-p...)
Affinity DataIC50: 420nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110307((3-Methyl-quinolin-4-yl)-(3-piperidin-1-yl-propyl)...)
Affinity DataIC50: 590nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110292(Methyl-(2-piperidin-1-yl-ethyl)-(1,2,3,4-tetrahydr...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methyl-histamineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM27213(CHEMBL1795025 | 4-[3-(4-cyclopropanecarbonylphenox...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition against histamine-metabolizing enzyme Histamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine N-methyltransferase(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataIC50: 1.04E+4nMAssay Description:Compound was tested against histamine N-methyl-transferase in rat brain [EC 2.1.1.8](relative weak affinity on rat enzyme)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed