Compile Data Set for Download or QSAR
Report error Found 146 of ic50 data for polymerid = 50001321,50001322,50003932
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044104((6S,7R)-1-((R)-4-Acetoxy-5-methyl-3-methylene-6-ph...)
Affinity DataIC50: 0.5nMAssay Description:Tested in vitro in rat liver squalene synthase assay (RLSS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044103((6S,7R)-1-((R)-4-Acetoxy-5-methyl-3-methylene-6-ph...)
Affinity DataIC50: 0.660nMAssay Description:Tested in vitro in rat liver squalene synthase assay (RLSS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044100((6S,7R)-1-((R)-4-Acetoxy-5-methyl-3-methylene-6-ph...)
Affinity DataIC50: 0.870nMAssay Description:Tested in vitro in rat liver squalene synthase assay (RLSS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044102((6S,7R)-1-((R)-4-Acetoxy-5-methyl-3-methylene-6-ph...)
Affinity DataIC50: 1.80nMAssay Description:Tested in vitro in rat liver squalene synthase assay (RLSS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044101((6S,7R)-1-((R)-4-Acetoxy-5-methyl-3-methylene-6-ph...)
Affinity DataIC50: 4.5nMAssay Description:Tested in vitro in rat liver squalene synthase assay (RLSS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[(6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amin...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032850([3-([3,3']Bithiophenyl-5-ylmethoxy)-benzyl]-((E)-6...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[(6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-amin...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 30nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032853(2-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032856(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093887(dodecyl gallate | Dodecyl 3,4,5-trihydroxybenzoate...)
Affinity DataIC50: 61nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant rat SE(squalene epoxidase)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50093887(dodecyl gallate | Dodecyl 3,4,5-trihydroxybenzoate...)
Affinity DataIC50: 61nMAssay Description:Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032830({3-[(Dimethyl-o-tolyl-silanyl)-methoxy]-benzyl}-et...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032837(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032847(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of dog liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070337([3,3']Bithiophenyl-5-sulfonic acid [2-(3-{[((E)-6,...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070344(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032848((6,6-Dimethyl-hepta-2,4-diynyl)-{3-[(dimethyl-o-to...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291660([3-([3,3']Bithiophenyl-5-ylmethoxy)-benzyl]-ethyl-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288841((3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-ami...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032834(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50281098(2,2-dimethyl-3-[3,7,12-trimethyl-14-[3-methyl-3-(4...)
Affinity DataIC50: 110nMAssay Description:Compound was tested for its inhibitory activity against squalene epoxidase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032832(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032842({3-[(Benzyl-dimethyl-silanyl)-methoxy]-benzyl}-((E...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50240891(theasinensin A | 2-(2-{6-[5,7-dihydroxy-3-(3,4,5-t...)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070341(Pyridine-3-sulfonic acid [2-(3-{[((E)-6,6-dimethyl...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032844(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032840(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(2-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070345(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070343(Thiazole-2-sulfonic acid [2-(3-{[((E)-6,6-dimethyl...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070350(N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethy...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070331(4-Cyano-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070346([2,3']Bithiophenyl-5-sulfonic acid [2-(3-{[((E)-6,...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032835((3-{[(4-Bromo-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070342(Thiophene-2-sulfonic acid cyclopropyl-[2-(3-{[((E)...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070349(Thiophene-3-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070333(N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethy...)
Affinity DataIC50: 255nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291661([3-(3-Azido-phenyl)-prop-2-ynyl]-[3-([3,3']bithiop...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]m...More data for this Ligand-Target Pair
In DepthDetails Article

TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070348(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-{3-[3-(t...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070339(4-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070347(4-Bromo-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070338(5-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50: 390nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50032831((3-{[(4-Chloro-phenyl)-dimethyl-silanyl]-methoxy}-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070335(Thiophene-2-sulfonic acid [2-(3-{[((E)-6,6-dimethy...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene monooxygenase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataIC50: 470nMAssay Description:Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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