Compile Data Set for Download or QSAR
Report error Found 17 of ic50 data for polymerid = 50000881,50003030
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHA8 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EphA8 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHA8 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHA8 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 75.2nMAssay Description:Inhibition of human EPHA8 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50584720(CHEMBL5088153)
Affinity DataIC50: 101nMAssay Description:Inhibition of human EphA8 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 137nMAssay Description:Inhibition of human EPHA8 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 233nMAssay Description:Inhibition of recombinant human EphA8 (615 to 911 residues) using KTFCGTPEYLAPE as substrate after 40 mins in presence of [gamma-33P]-ATP by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50: 434nMAssay Description:Inhibition of EPHA8 relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human EPHA8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50428059(CHEMBL2322989)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of ephrin-A1-Fc from EphA8 receptor Fc ectodomain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: 7.70E+3nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from mouse EphA8 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-tagged EPHA8 cytoplasmic domain (565 to 1005 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EPHA8 using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human EPhA8 (615 to 911 residues) at 1 uM using KTFCGTPEYLAPE as substrate incubated for 40 mins in presence of [gamma-33PA...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human GST-tagged cytoplasmic EPHA8 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged EPHA8 catalytic domain (565 to 1005 residues) expressed in baculovirus expression system using tyrosine-2 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed