Report error Found 151 of ic50 data for polymerid = 50000393
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal 6-his tagged TEV fused full length human NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-Codonplus(DE3)-RIL cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of NTMT1 in HEK293 cells assessed as reduction in me3-RCC1 level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of NTMT1 in HEK293 cells assessed as reduction in me3-SET level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assayMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assayMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminal 6-his tagged TEV fused full length human NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-Codonplus(DE3)-RIL cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assayMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assayMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assayMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human NTMT1 in human HCT116 cells assessed as reduction in me3-RCC1 level incubated for 72 hrs by western blot analysisMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human NTMT1 in human HCT116 cells assessed as reduction in me3-SET level incubated for 72 hrs by western blot analysisMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal 6-his tagged TEV fused full length human NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-Codonplus(DE3)-RIL cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of NTMT1 in HEK293 cells assessed as reduction in me3-RCC1 level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of NTMT1 in HEK293 cells assessed as reduction in me3-SET level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assayMore data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 414nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of full length His-NTMT1 (1 to 222 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as SAH production by Mtase...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 485nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of full length NTMT1 (1 to 222 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as SAH production by SAHH-coup...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of full length NTMT1 (1 to 222 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as SAH production by SAHH-coup...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of full length NTMT1 (1 to 222 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as SAH production by SAHH-coup...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of full length NTMT1 (1 to 222 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using GPKRIA as substrate preincubated ...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of N-terminal 6-his tagged TEV fused full length human NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-Codonplus(DE3)-RIL cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of N-terminal 6-his tagged TEV fused full length human NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-Codonplus(DE3)-RIL cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
