Compile Data Set for Download or QSAR
Report error Found 12 of ic50 data for polymerid = 50000361,50003816
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50241296(Zerumbone | CHEMBL245412)
Affinity DataIC50: 910nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50240978(5,6-dihydroxy-8,9-dihydro-1H-indolo[2,3-a]pyrrolo[...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50240682(2,10-dihydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50240964(2-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Mouse)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50249102(4-(3,4,5-tri(pyridin-4-yl)thiophen-2-yl)pyridine |...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GLI1/GLI2 in mouse Shh Light2 cells assessed as reduction in endogenous hedgehog signalling in presence of Smo agonist SAG by luciferas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50293858((S)-2-(3-Benzoylphenyl)-N,N-bis(4-hydroxyphenethyl...)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of exogenously transfected human Gli2 delta-N-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50321859(2-(3-Benzoylphenyl)-N-(1H-indol-5-yl)-N-propylprop...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human Gli2 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50293859((S)-2-(3-Benzoylphenyl)-N-(4-hydroxyphenethyl)-N-p...)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of exogenously transfected human Gli2 delta-N-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50321858(2-(3-Benzoylphenyl)-N-(1H-indol-6-yl)-N-propylprop...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human Gli2 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50293860((S)-2-(3-Benzoylphenyl)-N-(3,4-dihydroxyphenethyl)...)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of exogenously transfected human Gli2 delta-N-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50293861((S)-2-(3-Benzoylphenyl)-N-(4-hydroxyphenethyl)prop...)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of exogenously transfected human Gli2 delta-N-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed