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TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50503131(CHEMBL4563142)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606735(CHEMBL5219718 | US11731973, Example 3)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606737(CHEMBL5218727 | US11731973, Example 5)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606736(CHEMBL5218916 | US11731973, Example 10)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606741(CHEMBL5219710 | US11731973, Example 1)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50328584(1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606733(CHEMBL5218988)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606739(CHEMBL5220152 | US11731973, Example 7)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606740(CHEMBL5220536 | US11731973, Example 30)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50348452(CHEMBL1801204 | US9102670, 1a | AZD-8055)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606742(CHEMBL5220948 | US11731973, Example 9)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM35587(pyrazolo pyrimidine, 19)
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529393(CHEMBL4564479 | US11731973, Example 24)
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM315477(US10172858, Table 1.22 | US10172858, Table 1.1)
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630760(CHEMBL5433283)
Affinity DataIC50: 5nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606738(CHEMBL5218590 | US11731973, Example 6)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM582479(US11518767, Example 4 | 5-(2-aminobenzoxazol-5-yl)...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630757(CHEMBL5427469)
Affinity DataIC50: 7nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630747(CHEMBL5424319)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630759(CHEMBL5416106)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50328584(1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunob...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50310989((5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORC2 in human HEK293 cells assessed as decrease in phosphorylated Akt level incubated for 30 mins by immunoblot assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529395(CHEMBL4529672 | US11731973, Example 21)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM582478(US11518767, Example 3 | 5-(2-aminobenzoxazol-5-yl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630756(CHEMBL5410824)
Affinity DataIC50: 12nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630755(CHEMBL5420465)
Affinity DataIC50: 13nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630754(CHEMBL5404567)
Affinity DataIC50: 14nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50535043(CHEMBL4577549)
Affinity DataIC50: 15nMAssay Description:Inhibition of mTORC2 in HEK293T/17 cells assessed as reduction in Akt phosphorylation at Ser-473 residue after 2 hrs by sandwich immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606734(CHEMBL5221072)
Affinity DataIC50: 16nMAssay Description:Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546183(CHEMBL4744705)
Affinity DataIC50: 17nMAssay Description:Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630744(CHEMBL5404042)
Affinity DataIC50: 17nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630758(CHEMBL5399022)
Affinity DataIC50: 18nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529407(CHEMBL4572049)
Affinity DataIC50: 20nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50529398(CHEMBL4549761 | US11731973, Example 31)
Affinity DataIC50: 20nMAssay Description:Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630743(CHEMBL5425570)
Affinity DataIC50: 21nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630745(CHEMBL5394726)
Affinity DataIC50: 26nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630742(CHEMBL5400543)
Affinity DataIC50: 30nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606761(CHEMBL5220263)
Affinity DataIC50: 32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606762(CHEMBL5218550)
Affinity DataIC50: 32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606763(CHEMBL5219551)
Affinity DataIC50: 32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606764(CHEMBL5220568)
Affinity DataIC50: 32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50606765(CHEMBL5219300)
Affinity DataIC50: 32nMAssay Description:Inhibition of mTORC2 in human MDA-MB-468 cells assessed as measuring phosphorylated AKT incubated for 2 to 4 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50546183(CHEMBL4744705)
Affinity DataIC50: 34nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50515198(CHEMBL4445573)
Affinity DataIC50: 35nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50516024(CHEMBL4540705)
Affinity DataIC50: 38nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50431522(CHEMBL2348865)
Affinity DataIC50: 40nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50630737(CHEMBL5395211)
Affinity DataIC50: 42nMAssay Description:Inhibition of mTORC2 in human PC-3 cells assessed as AKT phosphorylation at S473 residue in incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50431521(CHEMBL2348864)
Affinity DataIC50: 46nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
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