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TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279436(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106179(Enantiomer-4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(2,...)
Affinity DataIC50: 2nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279740(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279471(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106169(Enantiomer-4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(2,...)
Affinity DataIC50: 9nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279454(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106167(Enantiomer-4-(3-Cyclopropylmethyl-[1,2,4]oxadiazol...)
Affinity DataIC50: 18nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106167(Enantiomer-4-(3-Cyclopropylmethyl-[1,2,4]oxadiazol...)
Affinity DataIC50: 18nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279703(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 22nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106178(4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(3,3-dimethyl-...)
Affinity DataIC50: 23nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106168(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-(3...)
Affinity DataIC50: 27nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106168(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-(3...)
Affinity DataIC50: 27nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279453(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 27nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061218((E)-3-(2,4-Dichloro-phenyl)-N-((R)-1-methyl-2-oxo-...)
Affinity DataIC50: 31nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106176(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-[5...)
Affinity DataIC50: 40nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106176(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-[5...)
Affinity DataIC50: 40nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279717(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 73nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50099582(N-[(3R,4S)-3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106182(N-(3,3-Dimethyl-butyl)-4-(3-phenyl-[1,2,4]oxadiazo...)
Affinity DataIC50: 130nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117913(1-{[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-amino...)
Affinity DataIC50: 240nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106166(N-(3,3-Dimethyl-butyl)-4-hexyloxy-benzamide | CHEM...)
Affinity DataIC50: 250nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106177(N-(3,3-Dimethyl-butyl)-4-indol-1-yl-benzamide | CH...)
Affinity DataIC50: 260nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279456(1-(2,3-dihydro-6-methylchromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 304nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279719(1-(2,3-dihydro-6-amidecarboxylchromen-4-ylideneami...)
Affinity DataIC50: 330nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106184(N-(3,3-Dimethyl-cyclopentyl)-4-hexyloxy-benzamide ...)
Affinity DataIC50: 360nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106180(N-(3,3-Dimethyl-cyclohexylmethyl)-4-hexyloxy-benza...)
Affinity DataIC50: 370nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106181(Biphenyl-4-carboxylic acid (3,3-dimethyl-butyl)-am...)
Affinity DataIC50: 540nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106164(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-(3...)
Affinity DataIC50: 580nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106164(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-(3...)
Affinity DataIC50: 580nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279700(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 650nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106175(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-he...)
Affinity DataIC50: 710nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106175(Enantiomer-N-(2,2-Dimethyl-cyclopentylmethyl)-4-he...)
Affinity DataIC50: 710nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371391(SENICAPOC)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of voltage-gated K channel 7.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279741(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279739(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279455(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279702(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106174(N-(2,2-Dimethyl-cyclohexylmethyl)-4-hexyloxy-benza...)
Affinity DataIC50: 1.40E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50254401(CHEMBL4093377)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of KCNQ1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50254387(CHEMBL4062193)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of KCNQ1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50395464(CHEMBL2164048)
Affinity DataIC50: 2.92E+3nMAssay Description:Antagonist activity at KCNQ1 expressed in CHO cells incubated for 3 mins by automated patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50254388(CHEMBL4101680)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of KCNQ1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106174(N-(2,2-Dimethyl-cyclohexylmethyl)-4-hexyloxy-benza...)
Affinity DataIC50: 3.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106165((3-tert-Butyl-pyrrolidin-1-yl)-(4-hexyloxy-phenyl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106170(N-(2-Diethylamino-ethyl)-4-hexyloxy-benzamide | CH...)
Affinity DataIC50: 3.50E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106183(1-(4-Hexyloxy-phenyl)-3-piperidin-1-yl-propan-1-on...)
Affinity DataIC50: 4.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106227((3R,4S)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106173(N,N-Diethyl-2-[4-(1,1,3,3-tetramethyl-butyl)-pheno...)
Affinity DataIC50: 5.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106171(Diethyl-{2-[4-(1,1,3,3-tetramethyl-butyl)-phenoxy]...)
Affinity DataIC50: 5.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279433(1-(2,3-dihydro-6-hydroxychromen-4-ylideneamino)-3-...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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