Compile Data Set for Download or QSAR
Report error Found 115 of ic50 data for polymerid = 50000300,50003836,50005942
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300992((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-3-[(S)-3-(4-Fluoro-...)
Affinity DataIC50: 4nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300992((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-3-[(S)-3-(4-Fluoro-...)
Affinity DataIC50: 4nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300992((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-3-[(S)-3-(4-Fluoro-...)
Affinity DataIC50: 4nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300992((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-3-[(S)-3-(4-Fluoro-...)
Affinity DataIC50: 4nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258479((2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorop...)
Affinity DataIC50: 7nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258479((2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorop...)
Affinity DataIC50: 16nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258479((2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorop...)
Affinity DataIC50: 20nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300992((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-3-[(S)-3-(4-Fluoro-...)
Affinity DataIC50: 44nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNPC1-like intracellular cholesterol transporter 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50: 127nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50: 150nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50: 173nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50: 200nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50240720((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-1-(4-Fluoro-phenyl)...)
Affinity DataIC50: 300nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50240720((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-1-(4-Fluoro-phenyl)...)
Affinity DataIC50: 300nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50371521(EZETIMIBE)
Affinity DataIC50: 370nMAssay Description:Inhibition of NPC1L1 (unknown origin) assessed as inhibition of cholesterol cellular uptake by BCA colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258548((1-(1-naphthoyl)-5-phenylpiperidin-3-yl)(spiro[ind...)
Affinity DataIC50: 390nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50240720((2S,3S,4S,5R,6S)-6-(4-{(2S,3R)-1-(4-Fluoro-phenyl)...)
Affinity DataIC50: 580nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332397(2,2,6,6-tetramethylpiperidin-4-yl 2-(8-(4-cyclohex...)
Affinity DataIC50: 600nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258480(((2S,4S)-1-benzoyl-4-phenylpyrrolidin-2-yl)(spiro[...)
Affinity DataIC50: 660nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332389(ethyl 1-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phenyl...)
Affinity DataIC50: 900nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332437(tert-butyl 4-(2-(8-(4-tert-butylbenzoyl)-4-oxo-1-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332404(2-(8-(4-tert-butylbenzoyl)-4-oxo-1-phenyl-1,3,8-tr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332446(8-(4-cyclohexylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332452(8-(4-cyclohexylbenzoyl)-3-(2-(4-(hydroxymethyl)pip...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332396(2,2,6,6-tetramethylpiperidin-4-yl 2-(8-(4-tert-but...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332429(tert-butyl(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phen...)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332426(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phenyl-1,3,8-tr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332435(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phenyl-1,3,8-tr...)
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258510(8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332424(methyl 4-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-pheny...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258510(8-(4-tert-butylbenzoyl)-3-(2-oxo-2-(piperidin-1-yl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332400(8-(4-tert-butylbenzoyl)-3-(2-(4-(1,3-diethyl-4-met...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332385(tert-butyl(1-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-p...)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332450(8-(4-cyclohexylbenzoyl)-3-(2-(3-ethylpiperidin-1-y...)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332453(8-(4-tert-butylbenzoyl)-3-(2-(4-(2-hydroxyethyl)pi...)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332395(1-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phenyl-1,3,8...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332434(N-(3-aminopropyl)-2-(8-(4-cyclohexylbenzoyl)-4-oxo...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332388(ethyl 1-(2-(8-(4-tert-butylbenzoyl)-4-oxo-1-phenyl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332417(2-(8-(4-tert-butylbenzoyl)-4-oxo-1-phenyl-1,3,8-tr...)
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332393(1-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phenyl-1,3,8...)
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332438(tert-butyl 4-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-p...)
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332448(8-(4-cyclohexylbenzoyl)-3-(2-(3-methylpiperidin-1-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332422(methyl 2-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-pheny...)
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332436(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-phenyl-1,3,8-tr...)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332433(N-(2-aminoethyl)-2-(8-(4-cyclohexylbenzoyl)-4-oxo-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332387(tert-butyl(1-(2-(8-(4-cyclohexylbenzoyl)-4-oxo-1-p...)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332449(8-(4-tert-butylbenzoyl)-3-(2-(3-ethylpiperidin-1-y...)
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332451(8-(4-tert-butylbenzoyl)-3-(2-(4-(hydroxymethyl)pip...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNPC1-like intracellular cholesterol transporter 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332414(N-(3-aminopropyl)-2-(8-(4-tert-butylbenzoyl)-4-oxo...)
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 115 total ) | Next | Last >>
Jump to: