Compile Data Set for Download or QSAR
Report error Found 48 of ic50 data for polymerid = 50000129,50006943
TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112170(CHEMBL3608425)
Affinity DataIC50: 6nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112167(CHEMBL3608428)
Affinity DataIC50: 6nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190487(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190466(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190462(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 8nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112171(CHEMBL3608426)
Affinity DataIC50: 9nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190494(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 9nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190486(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112172(CHEMBL3608427)
Affinity DataIC50: 13nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190481(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190459(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190468(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190484(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112169(CHEMBL3608424)
Affinity DataIC50: 20nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190489((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190475(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190465(1-(4-(4-aminophenyl)butyl)-3-(3,5-diamino-2-chloro...)
Affinity DataIC50: 21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190458(sulfuric acid mono-(4-{4-[N-(3,5-diamino-6-chlorop...)
Affinity DataIC50: 21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190488(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 22nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190480(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190490(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 26nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190493(N-(3,5-diamino-6-chloropyrazine-2-carbony)-N'-{4-[...)
Affinity DataIC50: 28nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190456(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190471(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190455(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190478(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190460(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[2-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190457(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190483((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 48nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190479(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190477(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50: 51nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190461(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(6-...)
Affinity DataIC50: 58nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190463(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[2-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190464(1-(3,5-diamino-2-chloropyrazine-6-carbonyl)-3-(5-(...)
Affinity DataIC50: 64nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190485(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-phe...)
Affinity DataIC50: 66nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM81819(NSC_108107 | CHEMBL212579 | CAS_1937-37-7 | Benzam...)
Affinity DataIC50: 66nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190470(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(5-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mouse)
Temple University

Curated by ChEMBL
LigandPNGBDBM50112168(CHEMBL3608423)
Affinity DataIC50: 70nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190474(6-(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbon...)
Affinity DataIC50: 73nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190495(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[5-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190491(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-hex...)
Affinity DataIC50: 87nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190472(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190473(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(2-...)
Affinity DataIC50: 107nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190492(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-oct...)
Affinity DataIC50: 108nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190482(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[3-...)
Affinity DataIC50: 124nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM115076(cid_9604979 | 3,5-diamino-N-[amino(anilino)methyli...)
Affinity DataIC50: 401nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190469(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(8-...)
Affinity DataIC50: 477nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataIC50: 776nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed