Compile Data Set for Download or QSAR
Report error Found 39 of ic50 data for polymerid = 50000010,50000087,50000532
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044989((O10eq)-beta-guanidinopropionylryanodine | CHEMBL2...)
Affinity DataIC50: 1.10nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044982(CHEMBL283836 | GLYCYLRYANODINE)
Affinity DataIC50: 1.80nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044986((O10eq)-guanidino acetylryanodine | CHEMBL435362)
Affinity DataIC50: 1.80nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044994(Ryanodine | 2,6,9,11,13,14-hexahydroxy-11-isopropy...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 2 hr by com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044995((O10eq)-beta-alanylryanodine | CHEMBL282089)
Affinity DataIC50: 2.60nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50051434(Ryanodine Derivative | 10-epi-hydroxy-Ryanodine | ...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against ryanodine receptor from mouse brain preparationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044994(Ryanodine | 2,6,9,11,13,14-hexahydroxy-11-isopropy...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 1 hr by com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50051434(Ryanodine Derivative | 10-epi-hydroxy-Ryanodine | ...)
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against ryanodine receptor from rabbit muscle preparationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044993(Benzyloxycarbonyl-glycylryanodine | CHEMBL28383)
Affinity DataIC50: 4.80nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044990((O10eq)-Benzyloxycarbonyl-beta-alanylryanodine | C...)
Affinity DataIC50: 5.90nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044994(Ryanodine | 2,6,9,11,13,14-hexahydroxy-11-isopropy...)
Affinity DataIC50: 6.20nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044991(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)
Affinity DataIC50: 8.90nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044994(Ryanodine | 2,6,9,11,13,14-hexahydroxy-11-isopropy...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016403(CHEMBL350293 | 2,6,9,11,13,14-hexahydroxy-11-isopr...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016410(CHEMBL163108 | 2,6,9,11,13,14-hexahydroxy-11-(2-hy...)
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044987((O10eq)-beta-N,N'-Bis-Benzyloxycarbonyl-guanidinop...)
Affinity DataIC50: 44nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044988(N-methyl ryanodine-succinamidate | CHEMBL432278)
Affinity DataIC50: 49nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016413(CHEMBL352124 | 2,6,9,11,13,14-hexahydroxy-11-isopr...)
Affinity DataIC50: 88nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016418(CHEMBL348796 | 6,9,11,13,14-pentahydroxy-11-isopro...)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044984(Di-Benzyloxycarbonyl-guanidino acetylryanodine | C...)
Affinity DataIC50: 136nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016411(2',6',9',11',13',14'-hexahydroxy-11'-isopropyl-7',...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016416(CHEMBL352211 | 6,9,11,13,14-pentahydroxy-11-isopro...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044992((O10eq)-beta-alanyl-anhydro-ryanodine | CHEMBL2826...)
Affinity DataIC50: 149nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016406(2,6,11,13,14-pentahydroxy-11-isopropyl-9-methoxy-3...)
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016417(CHEMBL349122 | 2,6,9,11,13,14-hexahydroxy-11-isopr...)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016405(CHEMBL348725 | 2,6,9,11,13,14-hexahydroxy-11-isopr...)
Affinity DataIC50: 860nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044991(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044991(2,6,9,11,13,14-hexahydroxy-11-isopropyl-7,10-dimet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50044985(ryanodine-hemi-succinate)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity for sarcoplasmic reticular calcium release channel (SR CRC) of rabbit skeletal membrane vesiclesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016412(2,11,13,14-tetrahydroxy-11-isopropyl-6,9-dimethoxy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016409(2,6,11,14-tetrahydroxy-11-isopropyl-9,13-dimethoxy...)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016404(CHEMBL354013 | 2,3,6,9,11,13,14-heptahydroxy-3-hyd...)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50191280(5,21-Dibromo-4-hydroxy-2-oxa-10,14-diaza-tricyclo[...)
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity to RYR1 channels by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016414(6,9,11,13,14-pentahydroxy-11-isopropyl-3,7,10-trim...)
Affinity DataIC50: 7.30E+3nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016408(CHEMBL164257 | 2,6,8,12-tetrahydroxy-10-isopropyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016402(CHEMBL353358 | 11-isopropyl-7,10-dimethyl-3-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016420(CHEMBL433518 | 2,6,9,11,13,14-hexahydroxy-11-isopr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016407(6,11,14-trihydroxy-11-isopropyl-2,9,13-trimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRyanodine receptor 1(Rabbit)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50016415(CHEMBL163458 | 11-isopropyl-3,7,10-trimethyl-(1R,2...)
Affinity DataIC50: 3.50E+4nMAssay Description:Displacement of [3H]ryanodine from Ca2+-ryanodine receptor in Oryctolagus cuniculus (rabbit) skeletal muscle sarcoplasmic reticulum after 80 min by c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed