Compile Data Set for Download or QSAR
Report error Found 3 of ic50 data for polymerid = 49000987,50002151,50006935,50007539
TargetP2X purinoceptor(Rhesus macaque)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM254266(US9464084, 158 | US10112937, Example 158 | US10150...)
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at macaque P2X7 assessed as inhibition of BzATP-induced calcium flux preincubated for 30 mins followed by BzATP addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor(Guinea pig)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50087267((S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-ox...)
Affinity DataIC50: 130nMAssay Description:Inhibition of guinea pig P2X7 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2X purinoceptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM85043(CHEMBL69234 | CAS_149017-66-3 | NSC_6093163 | PPAD...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of inward ion current elicited by ATP at mouse P2X4 receptor (mutant type)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed