Compile Data Set for Download or QSAR
Report error Found 320 of ic50 data for polymerid = 49000933,50001121
LigandPNGBDBM50371391(SENICAPOC)
Affinity DataIC50: 6nMAssay Description:Inhibition of Kca 3.1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50547905(CHEMBL4744833 | US20240034717, Example 31.60 | US1...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50547897(CHEMBL4749039 | US20240034717, Example 31.31 | US1...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50547904(CHEMBL4791725 | US20240034717, Example 31.57 | US1...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50099566(2-(4-Fluoro-phenyl)-2-(2-fluoro-phenyl)-2-phenyl-a...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371390(CHEMBL272039)
Affinity DataIC50: 10nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371391(SENICAPOC)
Affinity DataIC50: 12nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371385(CHEMBL260736)
Affinity DataIC50: 13nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371388(CHEMBL270704)
Affinity DataIC50: 14nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371389(CHEMBL272040)
Affinity DataIC50: 14nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50547898(CHEMBL4788143 | US20240034717, Example 31.37 | US1...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50547898(CHEMBL4788143 | US20240034717, Example 31.37 | US1...)
Affinity DataIC50: 14nMAssay Description:Human blood was drawn from healthy human volunteers in a standard heparinized blood sampling vial (Vacutainer, Li/heparin, BD Bioscience, Plymouth, U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50371382(CHEMBL408700)
Affinity DataIC50: 15nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371384(CHEMBL270071)
Affinity DataIC50: 15nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371395(CHEMBL273092)
Affinity DataIC50: 15nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM314248(US9611232, Example 13)
Affinity DataIC50: 15nMAssay Description:Compounds were tested using a PatchXpress (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM314285(US9611232, Example 17)
Affinity DataIC50: 15nMAssay Description:Compounds were tested using a PatchXpress (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM205030(process for preparing 2-(2-{2-[1-(2-fluorophenyl)-...)
Affinity DataIC50: 16nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50371386(CHEMBL260953)
Affinity DataIC50: 17nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM205069(process for preparing 5-{2-[2-(fluoromethyl)phenyl...)
Affinity DataIC50: 17nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50547900(CHEMBL4756080 | US20240034717, Example 31.47 | US1...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50547900(CHEMBL4756080 | US20240034717, Example 31.47 | US1...)
Affinity DataIC50: 18nMAssay Description:Human blood was drawn from healthy human volunteers in a standard heparinized blood sampling vial (Vacutainer, Li/heparin, BD Bioscience, Plymouth, U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50279107(1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole | C...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human cloned IK1 expressed in african green monkey COS7 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50279107(1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole | C...)
Affinity DataIC50: 20nMAssay Description:Inhibition of IK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371377(CHEMBL406683)
Affinity DataIC50: 20nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM314217(US9611232, Example 11)
Affinity DataIC50: 22nMAssay Description:Compounds were tested using a PatchXpress (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50547899(CHEMBL4764429 | US20240034717, Example 31.39 | US1...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50547899(CHEMBL4764429 | US20240034717, Example 31.39 | US1...)
Affinity DataIC50: 24nMAssay Description:Human blood was drawn from healthy human volunteers in a standard heparinized blood sampling vial (Vacutainer, Li/heparin, BD Bioscience, Plymouth, U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50371383(CHEMBL261828)
Affinity DataIC50: 30nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50371387(CHEMBL261606)
Affinity DataIC50: 30nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM205019(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 30nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50371396(CHEMBL270913)
Affinity DataIC50: 34nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM205016(process for preparing 5-[2-(2-ethoxyphenyl)phenyl]...)
Affinity DataIC50: 37nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50019902(CHEMBL3287207)
Affinity DataIC50: 39nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM200905(US9533999, i-39)
Affinity DataIC50: 39nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50371394(CHEMBL258604)
Affinity DataIC50: 40nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50019905(CHEMBL3287210 | US9533999, ii-4)
Affinity DataIC50: 41nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50019905(CHEMBL3287210 | US9533999, ii-4)
Affinity DataIC50: 41nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM314284(US9611232, Example 15)
Affinity DataIC50: 42nMAssay Description:Compounds were tested using a PatchXpress (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM314215(US9611232, Example 7)
Affinity DataIC50: 45nMAssay Description:Compounds were tested using a PatchXpress (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corpo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM200937(US9533999, ii-5)
Affinity DataIC50: 46nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM200946(US9533999, ii-8)
Affinity DataIC50: 47nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50547901(CHEMBL4745327 | US20240034717, Example 31.48 | US1...)
Affinity DataIC50: 47nMAssay Description:Inhibition of Kca3.1 in human erythrocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50547901(CHEMBL4745327 | US20240034717, Example 31.48 | US1...)
Affinity DataIC50: 47nMAssay Description:Human blood was drawn from healthy human volunteers in a standard heparinized blood sampling vial (Vacutainer, Li/heparin, BD Bioscience, Plymouth, U...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM50019903(CHEMBL3287208 | US9533999, i-40)
Affinity DataIC50: 48nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50019903(CHEMBL3287208 | US9533999, i-40)
Affinity DataIC50: 48nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50019900(CHEMBL3287205 | US9533999, i-5)
Affinity DataIC50: 49nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50019900(CHEMBL3287205 | US9533999, i-5)
Affinity DataIC50: 49nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50019904(CHEMBL3287209 | US9533999, ii-1)
Affinity DataIC50: 52nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50019904(CHEMBL3287209 | US9533999, ii-1)
Affinity DataIC50: 52nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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