Report error Found 480 of ic50 data for polymerid = 49000639,50001604
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human GlyT-2 expressed in CHO cells assessed as reduction in [3H]-glycine uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human GlyT2 stably expressed in CHO cells assessed as reduction in [3H]glycine uptake incubated for 10 mins by liquid scintillation cou...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GlyT2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human GlyT-2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake preincubated for 30 mins followed by 3H]-glycine ad...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human GlyT2 expressed in FreeStyle 293-F suspension cells incubated for 30 mins before [3H]glycine addition and measured af...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human GlyT-2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptakeMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Reversible inhibition of recombinant human GlyT2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake after 2 hrs by top count assa...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney
Curated by ChEMBL
University of Sydney
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
