Compile Data Set for Download or QSAR
Report error Found 56 of ic50 data for polymerid = 49000611,50002201
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599750(CHEMBL5180445)
Affinity DataIC50: 380nMAssay Description:Displacement of [3H]-HBT1 from GluA2-AMPA receptor (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599759(CHEMBL5199303)
Affinity DataIC50: 610nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599754(CHEMBL5197314)
Affinity DataIC50: 610nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611429(CHEMBL5270224)
Affinity DataIC50: 750nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599749(CHEMBL5171984)
Affinity DataIC50: 880nMAssay Description:Displacement of [3H]-HBT1 from GluA2-AMPA receptor (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253632(6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611434(CHEMBL5272105)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599748(CHEMBL5202949)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]-HBT1 from GluA2-AMPA receptor (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611436(CHEMBL5287234)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611433(CHEMBL5268367)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxali...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA2More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxali...)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human recombinant GLUA2-AMPA receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599756(CHEMBL5203039)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611439(CHEMBL5273228)
Affinity DataIC50: 4.30E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611435(CHEMBL5272421)
Affinity DataIC50: 5.50E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253650([1,2,5]oxadiazolo[3,4-g]quinoxaline-6,7(5H,8H)-dio...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of GluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611430(CHEMBL5270476)
Affinity DataIC50: 9.90E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611437(CHEMBL5266998)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611438(CHEMBL5272286)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611437(CHEMBL5266998)
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599764(CHEMBL5196410)
Affinity DataIC50: 1.90E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611446(CHEMBL5289868)
Affinity DataIC50: 2.10E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599755(CHEMBL5196482)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599760(CHEMBL5194021)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611440(CHEMBL5273106)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611441(CHEMBL5281996)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611442(CHEMBL5269221)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611432(CHEMBL5289176)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611443(CHEMBL5284167)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611444(CHEMBL5273123)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611445(CHEMBL5289396)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599758(CHEMBL5191480)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599751(CHEMBL5092058)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599766(CHEMBL5077022)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599763(CHEMBL5206364)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599762(CHEMBL5204122)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599761(CHEMBL5172392)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599765(CHEMBL5202402)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599757(CHEMBL5189104)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599753(CHEMBL5177597)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50599752(CHEMBL5192117)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50137125(2-(3-(3-bromophenyl)ureido)-4-chlorobenzoic acid |...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against Ionotropic glutamate receptor AMPA 2 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50158554({2-[3-(3-bromophenyl)ureido]-4-chlorophenyl}acetic...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50158555(1-[5-chloro-2-(5-oxo-4,5-dihydro-[1,2,4]oxadiazol-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50137125(2-(3-(3-bromophenyl)ureido)-4-chlorobenzoic acid |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50158561(2-[3-(3-bromophenyl)ureido]-4-chlorobenzenesulfoni...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50158556(1-(3-bromophenyl)-3-[5-chloro-2-(1H-tetrazol-5-yl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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