Compile Data Set for Download or QSAR
Report error Found 17 of ic50 data for polymerid = 49000601
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023573(4-Cyclohexyl-4-hydroxy-but-2-enoic acid | CHEMBL17...)
Affinity DataIC50: 3.30nMAssay Description:Binding affinity towards [3H]GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023572(Sodium; 4-hydroxy-but-2-enoate | CHEMBL354804)
Affinity DataIC50: 3.5nMAssay Description:Binding affinity towards [3H]GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023574(4-Hydroxy-pent-2-enoic acid | CHEMBL171595)
Affinity DataIC50: 11nMAssay Description:Binding affinity towards [3H]GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50246038((R)-2-(5-hydroxy-8,9-dihydro-5H-benzo[7]annulen-6(...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]SUC from succinic acid binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50246040(6,7,8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-y...)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]SUC from succinic acid binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50246038((R)-2-(5-hydroxy-8,9-dihydro-5H-benzo[7]annulen-6(...)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]GHB from gamma-hydroxybutyrate binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50246040(6,7,8,9-tetrahydro-5-hydroxy-5H-benzocyclohept-6-y...)
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]GHB from gamma-hydroxybutyrate binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50168281([3-(3-Phenyl-propoxy)-phenyl]-acetic acid | CHEMBL...)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023575(4-hydroxybutanoic acid | 4-hydroxybutyric acid | 4...)
Affinity DataIC50: 6.60E+3nMAssay Description:Binding affinity towards [3H]GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50168285((3-Phenethyloxy-phenyl)-acetic acid | CHEMBL190961)
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50168283((3-hydroxyphenyl)acetic acid | 3-hydroxyphenylacet...)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50060976((3-Phenoxy-phenyl)-acetic acid | CHEMBL107066)
Affinity DataIC50: 1.63E+4nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023575(4-hydroxybutanoic acid | 4-hydroxybutyric acid | 4...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50168282((3-Benzyloxy-phenyl)-acetic acid | CHEMBL190962)
Affinity DataIC50: 4.60E+4nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50246039((S,E)-2-(5-hydroxy-8,9-dihydro-5H-benzo[7]annulen-...)
Affinity DataIC50: 7.40E+4nMAssay Description:Displacement of [3H]SUC from succinic acid binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50246039((S,E)-2-(5-hydroxy-8,9-dihydro-5H-benzo[7]annulen-...)
Affinity DataIC50: 9.30E+4nMAssay Description:Displacement of [3H]GHB from gamma-hydroxybutyrate binding site of gamma-hydroxybutyrate receptor in rat forebrain synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGamma-hydroxybutyrate receptor(Rat)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50168284(4-Phenoxy-butyric acid | CHEMBL190723)
Affinity DataIC50: 2.10E+5nMAssay Description:Displacement of [3H]NCS-382 (16 nM) from GHB receptor of rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed