Compile Data Set for Download or QSAR
Report error Found 173 of ic50 data for polymerid = 4851,50000187
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263757((E)-3-(4-(3-(1-isopropylpiperidin-4-ylamino)phenyl...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264878(cis-4-{[2-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-e...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263657((cis)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263755((E)-3-(4-(3-(1-methylpiperidin-4-ylamino)phenylthi...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264880((trans)-4-((2-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263805((E)-1-morpholino-3-(4-(3-(1-propylpiperidin-4-ylam...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263806((E)-3-(4-(3-(8-methyl-8-azabicyclo[3.2.1]octan-3-y...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263710((trans)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263711((E)-1-morpholino-3-(4-(3-(piperidin-4-ylamino)phen...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263756((E)-3-(4-(3-(1-ethylpiperidin-4-ylamino)phenylthio...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50324826((2S)-2-(2,6-dichloro-4-(3-hydroxy-3-(3-hydroxyphen...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LFA1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263548((E)-3-(4-(3-aminophenylthio)-2,3-bis(trifluorometh...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318222(4-((5S,9R)-7-(5-(1H-Tetrazol-5-yl)pyridin-2-yl)-3-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265320((trans)-4-(2-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318219(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265147((E)-1-morpholino-3-(4-(2-(piperidin-4-yloxy)phenyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265190((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-thiopyran-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263656((trans)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265149((E)-1-morpholino-3-(4-(2-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264778(4-{(2E)-3-[4-{[2-(pyridin-3-ylmethoxy)phenyl]sulfa...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318220(6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107168(1-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(3-6)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265286((cis)-4-(3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263709((cis)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264879((cis)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-enyl)...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264881((trans)-4-((3-(4-((E)-3-morpholino-3-oxoprop-1-eny...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318228(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50264876((E)-1-morpholino-3-(4-(2-(pyridin-4-ylmethoxy)phen...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265148((E)-1-morpholino-3-(4-(3-(piperidin-4-yloxy)phenyl...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265285((cis)-4-(2-(4-((E)-3-morpholino-3-oxoprop-1-enyl)-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318231(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263596((E)-3-(4-(3-(methylamino)phenylthio)-2,3-bis(trifl...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318227(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318225(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318224(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107166(1-{3-[3-Chloro-4-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (4-7)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107169(1-{3-[4-(1-Methyl-1H-indol-5-ylsulfanyl)-2,3-bis-t...)
Affinity DataIC50: 5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(5-5)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107174(1-{3-[4-(2-Methoxy-phenylsulfanyl)-2,3-bis-trifluo...)
Affinity DataIC50: 5nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(4-6)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263708((E)-1-morpholino-3-(4-(3-(tetrahydro-2H-pyran-4-yl...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107173(1-{3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trif...)
Affinity DataIC50: 6nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (5-8)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107176(1-{3-[2,3-Dichloro-4-(1-methyl-1H-indol-5-ylsulfan...)
Affinity DataIC50: 6nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-6)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263707((E)-3-{4-[3-(1-Methylene-1-oxo-hexahydro-1lambda*6...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318226(2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107167(1-{3-[2,3-Dichloro-4-(2,3-dihydro-benzo[1,4]dioxin...)
Affinity DataIC50: 7nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-9)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107161(1-(4-Acetyl-piperazin-1-yl)-3-[2,3-dichloro-4-(2,3...)
Affinity DataIC50: 7nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range(6-9)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50263807((E)-3-(4-(3-(1-acetylpiperidin-4-ylamino)phenylthi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50318230(6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of LFA1-mediated adhesion of human T cells to ICAM1-expressing HUVEC by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107171(1-{3-[2,3-Dichloro-4-(2-methoxy-phenylsulfanyl)-ph...)
Affinity DataIC50: 8nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-12)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50107162(3-[3-Chloro-4-(2-methoxy-phenylsulfanyl)-2-trifluo...)
Affinity DataIC50: 8nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM-1) binding to recombinant LFA-1, range (6-10)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-L(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50265106((E)-3-(4-(2-(cyclohexyloxy)phenylthio)-2,3-bis(tri...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of recombinant LFA1/ICAM1-IG interaction by time-resolved fluorimetry methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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