Compile Data Set for Download or QSAR
Report error Found 52 of ic50 data for polymerid = 4840,50007698
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.0120nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at -100 mV by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at +100 mV by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519465(CHEMBL4466522)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fluo-4AM dye b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519473(CHEMBL4546097)
Affinity DataIC50: 46nMAssay Description:Inhibition of human TRPC4 expressed in human T-REx-293 cells coexpressing M1 receptor assessed as reduction in calcium influx by Fluo-4AM dye based a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50599832(CHEMBL5201831)
Affinity DataIC50: 65nMAssay Description:Inhibition of TRPC4 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intra...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50529421(CHEMBL4530872)
Affinity DataIC50: 290nMAssay Description:Inhibition of Englerin-activated human TRPC4 channel expressed in HEK293 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79626(2-(azepan-1-yl)-4,6-dimethylquinoline;2,2,2-triflu...)
Affinity DataIC50: 900nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | cid_230710 |...)
Affinity DataIC50: 960nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50519463(CHEMBL4532004)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse TRPC4 expressed in HEK293 cells coexpressing M5 receptor assessed as reduction in TRPC4-mediated calcium influx by fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79629(VU0206683-4 | 2-(azepan-1-yl)-6-fluoro-4-methylqui...)
Affinity DataIC50: 1.63E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79628(VU0204326-4 | 2-(azepan-1-yl)-4-methyl-quinoline;2...)
Affinity DataIC50: 1.96E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77625(cid_46891900 | VU0419900-1 | 6-ethyl-4-methyl-2-py...)
Affinity DataIC50: 2.05E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50595298(CHEMBL5207902)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of human TRPC4 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellula...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM72595(2-(azepan-1-yl)-7-methoxy-4-methylquinoline;oxalic...)
Affinity DataIC50: 2.38E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | cid_230710 |...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced current by QPatch cl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | cid_230710 |...)
Affinity DataIC50: 2.63E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77618(4-methyl-2-(4-methyl-1-piperidinyl)quinoline;2,2,2...)
Affinity DataIC50: 3.14E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79627(VU0424395-1 | 2-(azepan-1-yl)-6-ethyl-4-methyl-qui...)
Affinity DataIC50: 3.30E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77620(4-methyl-2-pyrrolidin-1-ylquinoline;2,2,2-trifluor...)
Affinity DataIC50: 3.59E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50492279(CHEMBL1376358)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced intracellular calciu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77624(4,6-dimethyl-2-pyrrolidin-1-ylquinoline;2,2,2-trif...)
Affinity DataIC50: 3.71E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79623(VU0419899-1 | cid_46891898 | 6-ethyl-4-methyl-2-(1...)
Affinity DataIC50: 3.73E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79624(6-fluoro-4-methyl-2-pyrrolidin-1-ylquinoline;2,2,2...)
Affinity DataIC50: 3.94E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50519474(CHEMBL4436705)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77621(VU0418910-1 | 4-methyl-2-[(2S)-2-methylpyrrolidin-...)
Affinity DataIC50: 4.26E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77614(SMR000122006 | MLS000529531 | 5-(4-fluorophenyl)-N...)
Affinity DataIC50: 4.28E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50492273(CHEMBL2396913)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77616(SMR000293019 | 4-chloro-N-cyclohexylbenzenecarboxi...)
Affinity DataIC50: 4.56E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50519475(CHEMBL4438838)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77623(cid_46891894 | 4,6-dimethyl-2-(1-piperidinyl)quino...)
Affinity DataIC50: 5.49E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50519468(CHEMBL4440241)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77626(cid_46891902 | 6-fluoro-4-methyl-2-(1-piperidinyl)...)
Affinity DataIC50: 6.18E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM85747(CLEMIZOLE HYDROCHLORIDE | NSC_2782 | CAS_442-52-4 ...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of YFP-tagged mouse TRPC4 beta expressed in thapsigargin treated HEK293 cells co-expressing M3 receptor assessed as reduction in carbachol...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79618(N,N-diethyl-4-methyl-quinolin-2-amine;2,2,2-tris(f...)
Affinity DataIC50: 7.54E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77622(4-methyl-2-(4-pyridin-4-ylpiperazin-1-yl)quinoline...)
Affinity DataIC50: 8.18E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50519472(CHEMBL4454499)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of mouse TRPC4 expressed in HEK293 cells coexpressing M5 receptor assessed as reduction in TRPC4-mediated calcium influx by fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79620(2-[4-(4-methyl-2-quinolinyl)-1-piperazinyl]benzoni...)
Affinity DataIC50: 8.90E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79622(1-(4-methylquinolin-2-yl)piperidin-3-ol;2,2,2-tris...)
Affinity DataIC50: 9.40E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79619(2-[4-(2-methoxyphenyl)piperazin-1-yl]-4-methylquin...)
Affinity DataIC50: 9.89E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79625(4,8-dimethyl-2-(1-pyrrolidinyl)quinoline;2,2,2-tri...)
Affinity DataIC50: 9.96E+3nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse TRPC4 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50450500(CHEMBL4164465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRPC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50239166(CHEMBL4083411)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR decrease in DAMGO-evoked intracellular calcium level by Fluo-8-AM ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50492280(CHEMBL2396911)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50492279(CHEMBL1376358)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50492274(CHEMBL2396912)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79617(2-(3,5-dimethylpiperidin-1-yl)-4-methyl-quinoline;...)
Affinity DataIC50: 1.19E+4nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM79621(VU0418913-1 | cid_46259350 | 4-(4-methyl-2-quinoli...)
Affinity DataIC50: 2.45E+4nMAssay Description:The inhibitory effects of test compounds on TRPC4 channels were evaluated in electrophysiological assays using a QPatch16 automated electrophysiology...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PCBioAssay
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM50239164(CHEMBL4080748)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR decrease in DAMGO-evoked intracellular calcium level by Fluo-8-AM ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM77615(SMR000199869 | cid_900782 | 2-phenyl-N-(2-phenylsu...)
Affinity DataIC50: 3.87E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
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