Compile Data Set for Download or QSAR
Report error Found 321 of ic50 data for polymerid = 4636,50003041
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of EphA4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human EPHA4 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50157880(CHEMBL3787112)
Affinity DataIC50: 9nMAssay Description:Inhibition of EphA4 (unknown origin) in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535195(CHEMBL4530593)
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535199(CHEMBL4462106)
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 12.5nMAssay Description:Inhibition of human EPHA4 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataIC50: 20nMAssay Description:Antagonist activity against mouse EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535194(CHEMBL4464855)
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535198(CHEMBL4440005)
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535186(CHEMBL4436732)
Affinity DataIC50: 27nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535192(CHEMBL4458170)
Affinity DataIC50: 34nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535196(CHEMBL4447628)
Affinity DataIC50: 38nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535193(CHEMBL4539149)
Affinity DataIC50: 40nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535184(CHEMBL4516686)
Affinity DataIC50: 41nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535182(CHEMBL4449863)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535200(CHEMBL4434643)
Affinity DataIC50: 54nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 70nMAssay Description:Inhibition of EPHA4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50452149(CHEMBL4216073)
Affinity DataIC50: 74nMAssay Description:Inhibition of EphA4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535181(CHEMBL4436577)
Affinity DataIC50: 83nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM378885(US10266537, Compound 93)
Affinity DataIC50: 227nMAssay Description:Inhibition of human recombinant EPHA4 (601 to 892 residues) using poly(Glu,Tyr)4:1 as substrate incubated for 40 mins in presence of [gamma33P-ATP] b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535197(CHEMBL4474623)
Affinity DataIC50: 230nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataIC50: 240nMAssay Description:Inhibition of 0.5 ug/ml ephrinA5-induced human EphA4 tyrosine phosphorylation expressed in HEK293AD cells preincubated for 20 mins followed by ephrin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535190(CHEMBL4520376)
Affinity DataIC50: 260nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535183(CHEMBL4569881)
Affinity DataIC50: 290nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM38802(MLS000038842 | SMR000040243 | cid_659226)
Affinity DataIC50: 300nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535195(CHEMBL4530593)
Affinity DataIC50: 310nMAssay Description:Inhibition of 0.4 ug/ml ephrinA5-induced human EphA4 tyrosine phosphorylation expressed in HEK293AD cells preincubated for 20 mins followed by ephrin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)furan-2-yl]methylidene]...)
Affinity DataIC50: 400nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535189(CHEMBL4442705)
Affinity DataIC50: 450nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535191(CHEMBL4522324)
Affinity DataIC50: 480nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM39775(SMR000174254 | MLS000557712 | 5-[3-(4-Dimethylamin...)
Affinity DataIC50: 600nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535188(CHEMBL4591478)
Affinity DataIC50: 920nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44521(SMR000184539 | MLS000573689 | cid_702952 | 2,3,6-t...)
Affinity DataIC50: 1.20E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50535187(CHEMBL4476251)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44528(MLS000575887 | cid_1327487 | SMR000196919 | 4-{[8-...)
Affinity DataIC50: 1.35E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44498(2-chloro-5-[5-[(Z)-(5-cyano-4-methyl-2,6-dioxo-3-p...)
Affinity DataIC50: 1.45E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44530(ethyl 3-oxidanylidene-7-phenyl-5-thiophen-2-yl-2-[...)
Affinity DataIC50: 1.49E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44520((4Z)-4-[[7-methyl-2-(4-morpholinyl)-3-quinolinyl]m...)
Affinity DataIC50: 1.54E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50618607(CHEMBL5425418)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of full length NanoLuc fused EPHA4 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in p...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44487(2-[(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[3-c...)
Affinity DataIC50: 1.79E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50359971(CHEMBL1927263)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of his-tagged EPHA4-mediated poly(Glu,Tyr) phosphorylation after 75 mins using E4:Y1 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40838(7-[(4-hydroxy-3,5-dimethoxyphenyl)-(2-pyridinylami...)
Affinity DataIC50: 2.02E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44463(cid_1375610 | ethyl 2-acetamido-6-methanoyl-7-phen...)
Affinity DataIC50: 2.26E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44506(1-Benzyl-3-(2-nitro-vinyl)-1H-indole | 3-[(E)-2-ni...)
Affinity DataIC50: 2.30E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM31751(MLS-0002046.0001 | cid_6400942 | 3-[(2-chloropheny...)
Affinity DataIC50: 2.46E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44504(cid_6522725 | ethyl 2-chloranyl-5-[5-[(E)-[5-cyano...)
Affinity DataIC50: 2.53E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44517((5Z)-3-phenylazanyl-2-sulfanylidene-5-[(3,4,5-trim...)
Affinity DataIC50: 2.64E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428059(CHEMBL2322989)
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of ephrin-A1-Fc from EphA4 receptor Fc ectodomain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM41028(cid_6375556 | 2-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-...)
Affinity DataIC50: 2.79E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM44470((5Z)-3-anilino-2-(4-methylphenyl)-5-(thiophen-2-yl...)
Affinity DataIC50: 2.91E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
Displayed 1 to 50 (of 321 total ) | Next | Last >>
Jump to: