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Report error Found 268 of ic50 data for polymerid = 4582,9828,50000297
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50355756(CHEMBL1909658)
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50355755(CHEMBL1911296)
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 20nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50355751(CHEMBL1911286)
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 30nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50355758(CHEMBL1911306)
Affinity DataIC50: 139nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592137(US11572337, Compound 0MTK149)
Affinity DataIC50: 140nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50355757(CHEMBL1911298)
Affinity DataIC50: 142nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592141(US11572337, Compound 0MTK158)
Affinity DataIC50: 220nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592173(US11572337, Compound 0MTK267)
Affinity DataIC50: 300nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592161(US11572337, Compound 0MTK237)
Affinity DataIC50: 310nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50155485({(E)-5-[5-((2E,4E)-2,5-Dimethyl-nona-2,4-dienoyl)-...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592133(US11572337, Compound 0MTK127)
Affinity DataIC50: 370nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592145(US11572337, Compound 0MTK176)
Affinity DataIC50: 390nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592132(US11572337, Compound 0MTK107)
Affinity DataIC50: 400nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592142(US11572337, Compound 0MTK174)
Affinity DataIC50: 410nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592138(US11572337, Compound 0MTK154)
Affinity DataIC50: 420nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592144(US11572337, Compound 0MTK175)
Affinity DataIC50: 450nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50355753(CHEMBL1911289)
Affinity DataIC50: 503nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins using ribo green staining by rolling circle transcription assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592146(US11572337, Compound 0MTK178)
Affinity DataIC50: 610nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592164(US11572337, Compound 0MTK256)
Affinity DataIC50: 650nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592135(US11572337, Compound 0MTK146)
Affinity DataIC50: 690nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592175(US11572337, Compound 0MTK269)
Affinity DataIC50: 700nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592159(US11572337, Compound 0MTK232)
Affinity DataIC50: 720nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592162(US11572337, Compound 0MTK238)
Affinity DataIC50: 770nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592166(US11572337, Compound 0MTK260)
Affinity DataIC50: 780nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592139(US11572337, Compound 0MTK155)
Affinity DataIC50: 790nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592136(US11572337, Compound 0MTK148)
Affinity DataIC50: 800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592165(US11572337, Compound 0MTK257)
Affinity DataIC50: 800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592174(US11572337, Compound 0MTK268)
Affinity DataIC50: 800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592140(US11572337, Compound 0MTK156)
Affinity DataIC50: 820nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592170(US11572337, Compound 0MTK264)
Affinity DataIC50: 820nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592147(US11572337, Compound 0MTK180)
Affinity DataIC50: 830nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50155484(CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...)
Affinity DataIC50: 920nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592134(US11572337, Compound 0MTK128)
Affinity DataIC50: 970nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50155487({(E)-5-[4-Hydroxy-5-((2E,4E)-2-methyl-nona-2,4-die...)
Affinity DataIC50: 1.04E+3nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592172(US11572337, Compound 0MTK266)
Affinity DataIC50: 1.20E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50155484(CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...)
Affinity DataIC50: 1.26E+3nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592169(US11572337, Compound 0MTK263)
Affinity DataIC50: 1.30E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592171(US11572337, Compound 0MTK265)
Affinity DataIC50: 1.30E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592148(US11572337, Compound 0MTK181)
Affinity DataIC50: 1.40E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592167(US11572337, Compound 0MTK261)
Affinity DataIC50: 1.50E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592168(US11572337, Compound 0MTK262)
Affinity DataIC50: 1.50E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592149(US11572337, Compound 0MTK183)
Affinity DataIC50: 1.70E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM228835(MRL-436)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
The Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50491557(CHEMBL2046886)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rifamycin-resistant Escherichia coli RNA polymerase D516V mutant after 10 mins by rolling circle transcription assay in presence of DNA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592163(US11572337, Compound 0MTK240)
Affinity DataIC50: 2.10E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM50155484(CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM228835(MRL-436)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandPNGBDBM592176(US11572337, Compound 3RKHTK161)
Affinity DataIC50: 3.30E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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