Compile Data Set for Download or QSAR
Report error Found 391 of ic50 data for polymerid = 4516,50006834
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124354(CHEMBL3623439)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50611804(CHEMBL5278261)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50299583((S)-N-(3-bromophenyl)-N'-cyano-2-methyl-4-(5-methy...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124355(CHEMBL3623442)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50611805(CHEMBL5275331)
Affinity DataIC50: 1nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM199250(US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human LIMK1 using cofilin as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human LIMK1 using cofilin as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124400(CHEMBL3623438)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124352(CHEMBL3623441)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124400(CHEMBL3623438)
Affinity DataIC50: 3nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50299584((S)-N-(3-bromo-4-fluorophenyl)-N'-cyano-2-methyl-4...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124399(CHEMBL3623437)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50327391(N1-(4-(2-chlorophenyl)-6-(2-(isopropylamino)thiazo...)
Affinity DataIC50: 4.01nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124397(CHEMBL3623435)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591311(CHEMBL3182065)
Affinity DataIC50: 5nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124397(CHEMBL3623435)
Affinity DataIC50: 5nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50299586((S)-3-(2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrim...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant LIMK1(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50299585((S)-N-(3-bromo-4-fluorophenyl)-2-methyl-4-(5-methy...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 7nMAssay Description:Inhibition of human glutathione S-transferase-tagged LIMK1 (321 to 647 residues) expressed in baculovirus-infected Sf9 cells incubated for 30 mins by...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 7nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50112355(CHEMBL3609326)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50072672(CHEMBL3410056)
Affinity DataIC50: 8nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124353(CHEMBL3623443)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50611806(CHEMBL5275515)
Affinity DataIC50: 8nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50611817(CHEMBL5289711)
Affinity DataIC50: 8nMAssay Description:Inhibition of LIMK1 (unknown origin) phosphorylation of cofilinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591091(CHEMBL5169387)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant full length LIMK1 (330 to 637 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50130039(CHEMBL3629276)
Affinity DataIC50: 10nMAssay Description:Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50130038(CHEMBL3629277)
Affinity DataIC50: 11nMAssay Description:Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant LIMK1 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human LIMK1 by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124363(CHEMBL3622874)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124363(CHEMBL3622874)
Affinity DataIC50: 13nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124356(CHEMBL3622867)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50124356(CHEMBL3622867)
Affinity DataIC50: 15nMAssay Description:Inhibition of human LIMK1 (321 to 647 residues) expressed in Sf9 cells using dextrin as substrate incubated for 30 mins by micro-scintillation fluid ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50117489(CHEMBL3613598)
Affinity DataIC50: 16nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591090(CHEMBL2141887)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50072662(CHEMBL3407526)
Affinity DataIC50: 18nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50117303(CHEMBL3613601)
Affinity DataIC50: 18nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50433630(CHEMBL2380834)
Affinity DataIC50: 18nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50591311(CHEMBL3182065)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLIM domain kinase 1(Human)
Cancer Research Technology

Curated by ChEMBL
LigandPNGBDBM50072671(CHEMBL3410055)
Affinity DataIC50: 19nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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