Compile Data Set for Download or QSAR
Report error Found 380 of ic50 data for polymerid = 4191
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM6863(US8815926, 101 | US8815926, 295)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human MDM4 by SRP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50513200(CHEMBL4514512)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241617(CHEMBL4068667)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM63209(SMR000206694 | 3-(1-phenyl-2-thioxo-2,3-dihydro-1H...)
Affinity DataIC50: 3.74nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241630(CHEMBL4065471)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241631(CHEMBL4095983)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617216(CHEMBL5410760)
Affinity DataIC50: 9nMAssay Description:Inhibition of human MDM4 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241627(CHEMBL4105199)
Affinity DataIC50: 10nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241621(CHEMBL4095042)
Affinity DataIC50: 11nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50287990(CHEMBL4165669)
Affinity DataIC50: 12nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50605104(CHEMBL5180980)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403528(CHEMBL5280843)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590815(CHEMBL5199785)
Affinity DataIC50: 18nMAssay Description:Inhibition of MDM4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241626(CHEMBL4080951)
Affinity DataIC50: 23nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590813(CHEMBL5204846)
Affinity DataIC50: 25nMAssay Description:Inhibition of MDM4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403525(CHEMBL3220312)
Affinity DataIC50: 25nMAssay Description:Inhibition of human MDM4More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403525(CHEMBL3220312)
Affinity DataIC50: 25nMAssay Description:Inhibition of MDM4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590814(CHEMBL5182359)
Affinity DataIC50: 27nMAssay Description:Inhibition of MDM4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50629225(CHEMBL5414695)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal biotin-his-tagged MDMX (24 to 108 residues)(unknown origin) binding to p53 incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50: 40nMAssay Description:Inhibition of human MDM4 by ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403482(CHEMBL5267044)
Affinity DataIC50: 41nMAssay Description:Inhibition of human MDM4More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50617215(CHEMBL5395151)
Affinity DataIC50: 43nMAssay Description:Inhibition of human MDM4 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241618(CHEMBL4064911)
Affinity DataIC50: 56nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50287896(CHEMBL4170132)
Affinity DataIC50: 58nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50629224(CHEMBL5421867)
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal biotin-his-tagged MDMX (24 to 108 residues)(unknown origin) binding to p53 incubated for 1 hr by Alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50: 77nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50287725(CHEMBL4162220)
Affinity DataIC50: 82nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241629(CHEMBL4100348)
Affinity DataIC50: 88nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339176(CHEMBL1689406)
Affinity DataIC50: 100nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403304(CHEMBL5268770)
Affinity DataIC50: 110nMAssay Description:Inhibition of human MDM4 by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM129732(US8815926, 11)
Affinity DataIC50: 120nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241623(CHEMBL4102803)
Affinity DataIC50: 136nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241622(CHEMBL4074577)
Affinity DataIC50: 140nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403529(CHEMBL5290391)
Affinity DataIC50: 145nMAssay Description:Inhibition of human MDM4 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM143511(US8969341, 126)
Affinity DataIC50: 150nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339177((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM129725(US8815926, 4)
Affinity DataIC50: 175nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM129731(US8815926, 10)
Affinity DataIC50: 179nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339178((2S,5S,8S,11S,14S,17S,20S,23S,26S)-23-((1H-imidazo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM143461(US8969341, 102)
Affinity DataIC50: 193nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241620(CHEMBL4073512)
Affinity DataIC50: 207nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339168(CHEMBL1689400)
Affinity DataIC50: 210nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50241628(CHEMBL4084848)
Affinity DataIC50: 215nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM129733(US8815926, 12)
Affinity DataIC50: 217nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50287986(CHEMBL4164619)
Affinity DataIC50: 219nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339163(N-((4S,7S,10S,13S,16S,19S,22S,25S)-16-((1H-imidazo...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM129730(US8815926, 9)
Affinity DataIC50: 229nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339167(N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S)-16-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339179((8S,11S,14S,17S,20S,23S,26S,29S)-26-((1H-imidazol-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein Mdm4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339174((2S,5S,8S,11S,14S,17S,20S,23S,26S)-17-((1H-indol-3...)
Affinity DataIC50: 282nMAssay Description:Inhibition of human GST-tagged MDMX expressed in Escherichia coli harboring integrated p53-Hmd2 protein assessed as blockade of enzyme-p53 interactio...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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