Compile Data Set for Download or QSAR
Report error Found 722 of ic50 data for polymerid = 3930,4170
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558852(CHEMBL4747465)
Affinity DataIC50: 6.5nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558851(CHEMBL4782684)
Affinity DataIC50: 6.60nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50210070(CHEMBL3883565)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of FITC-betaA-DIIRNIARHLAQVGDSMRSI-NH2 binding to recombinant human Bcl2A1 (1 to 152 residues) BH3 binding site expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558856(CHEMBL4791348)
Affinity DataIC50: 13nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558854(CHEMBL4755711)
Affinity DataIC50: 14nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50587033(CHEMBL5075478)
Affinity DataIC50: 18nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558857(CHEMBL4752520)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM333146(US10196404, Example 1 | Compound I | US10196404, E...)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal His6-tagged Bfl-1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli using Fluor 647-labeled BAK peptide WIA...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558853(CHEMBL4465826)
Affinity DataIC50: 31nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50558855(CHEMBL4740212)
Affinity DataIC50: 55nMAssay Description:Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50210069(CHEMBL3884841)
Affinity DataIC50: 110nMAssay Description:Inhibition of FITC-betaA-DIIRNIARHLAQVGDSMRSI-NH2 binding to recombinant human Bcl2A1 (1 to 152 residues) BH3 binding site expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50330250(5,5'-Dibenzyl-6,6',7,7'-tetrahydroxy-3,3'-dimethyl...)
Affinity DataIC50: 122nMAssay Description:Inhibition of FITC-labeled Bim BH3 binding to GST-tagged Bcl2A1 (unknown origin) preincubated for 2 mins followed by FITC-Bim-BH3 addition measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50330250(5,5'-Dibenzyl-6,6',7,7'-tetrahydroxy-3,3'-dimethyl...)
Affinity DataIC50: 122nMAssay Description:Inhibition of Bfl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50366237(GAMBOGIC ACID)
Affinity DataIC50: 176nMAssay Description:Inhibition of recombinant Bfl-1 (1-152) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39156(CHEMBL1272100 | MLS-0090874.0001 | 3-chloro-1-(3,4...)
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50313364((2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-4-methylphen...)
Affinity DataIC50: 250nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50587038(CHEMBL5090086)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50610578(CHEMBL5283854)
Affinity DataIC50: 264nMAssay Description:Inhibition of Bfl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39124(MLS-0067130.0001 | 3-chloranyl-1-(3,4-dichlorophen...)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39146(CHEMBL1272154 | 3-chloro-1-(3,4-dichlorophenyl)-4-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM41228(SMR000065994 | 2,3,5,6-tetrakis(2-furanyl)pyrazine...)
Affinity DataIC50: 360nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataIC50: 362nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM380468(US9926306, ID 183-21)
Affinity DataIC50: 365nMAssay Description:Inhibition of Bfl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31809(Apogossypol derivative, 8k)
Affinity DataIC50: 400nMT: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39124(MLS-0067130.0001 | 3-chloranyl-1-(3,4-dichlorophen...)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39146(CHEMBL1272154 | 3-chloro-1-(3,4-dichlorophenyl)-4-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50587036(CHEMBL5091695)
Affinity DataIC50: 400nMAssay Description:Inhibition of human Bfl-1 (1 to 149 residues) expressed in Rosetta-gami (DE3) using biotinylated-BH3 peptide as substrate measured after 2 hrs by DEL...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39124(MLS-0067130.0001 | 3-chloranyl-1-(3,4-dichlorophen...)
Affinity DataIC50: 419nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39146(CHEMBL1272154 | 3-chloro-1-(3,4-dichlorophenyl)-4-...)
Affinity DataIC50: 420nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31810(Apogossypol derivative, 8r)
Affinity DataIC50: 420nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50313335(6-(cyclohexylamino)-N-(4-sulfamoylphenyl)pyrimidin...)
Affinity DataIC50: 450nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39146(CHEMBL1272154 | 3-chloro-1-(3,4-dichlorophenyl)-4-...)
Affinity DataIC50: 470nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataIC50: 500nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39134(3,4-dichloro-1-(2,3-dichlorophenyl)pyrrole-2,5-dio...)
Affinity DataIC50: 500nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39124(MLS-0067130.0001 | 3-chloranyl-1-(3,4-dichlorophen...)
Affinity DataIC50: 540nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31805(Apogossypol derivative, 8n)
Affinity DataIC50: 550nMT: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM51914(2-(diethylamino)ethyl 4-[[(Z)-2-cyano-2-[4-(2-oxoc...)
Affinity DataIC50: 550nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39156(CHEMBL1272100 | MLS-0090874.0001 | 3-chloro-1-(3,4...)
Affinity DataIC50: 556nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39172(3-chloro-4-(4-ethyl-1-piperazinyl)-1-(4-nitropheny...)
Affinity DataIC50: 565nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataIC50: 580nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39156(CHEMBL1272100 | MLS-0090874.0001 | 3-chloro-1-(3,4...)
Affinity DataIC50: 590nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39149(MLS-0090859.0001 | 3-chloro-1-(3,4-dichlorophenyl)...)
Affinity DataIC50: 594nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39147(3-chloro-1-(3,4-dichlorophenyl)-4-[(3R)-3-methylpi...)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316672((R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-N5-((...)
Affinity DataIC50: 620nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM39156(CHEMBL1272100 | MLS-0090874.0001 | 3-chloro-1-(3,4...)
Affinity DataIC50: 620nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316672((R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-N5-((...)
Affinity DataIC50: 620nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Bfl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316672((R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-N5-((...)
Affinity DataIC50: 620nMAssay Description:Inhibition of BH3 peptide binding to Bfl-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM31810(Apogossypol derivative, 8r)
Affinity DataIC50: 620nMAssay Description:Inhibition of Bfl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataIC50: 650nMpH: 7.0 T: 2°CAssay Description:The aim is to identify chemical probes of Bfl-1 through a fluorescence polarization assay (FPA) using FITC-Bid BH3 peptide. 1) Dose-response curves c...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
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