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Report error Found 7233 of ic50 data for polymerid = 384,1129,50000884,50002482
TargetAmine oxidase [flavin-containing] A(Mouse)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50490813(CHEMBL2346911)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate incubated for 15 mins by Amplex red and horseradish peroxidase based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 0.00490nMAssay Description:Inhibition of human monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Mouse)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50188722(3-(3-trifluoromethyl)phenyl-8-methoxy-5H-indeno[1,...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of MAO-B in baboon liver mitochondriaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50603177(CHEMBL5200566)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50619026(CHEMBL5428315)
Affinity DataIC50: 0.103nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM174835(US9114126, 2027BA1)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of rat MAO-AMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50359391(CHEMBL1929421)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50046866(CHEMBL3319256)
Affinity DataIC50: 0.389nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50603180(CHEMBL5178014)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 0.5nMAssay Description:The compounds of the present invention obtained in the Production Examples were examined for the inhibitory effect on human monoamineoxydase enzymes ...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human full length recombinant MAO-A expressed in insect cells using kynuramine as substrateMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50619030(CHEMBL5395648)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50232425(CHEMBL4061639)
Affinity DataIC50: 0.661nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50327224(4-Benzyl-[1,2,4]triazolo[4,3-a]quinoxaline | CHEMB...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of MAO-A (unknown origin) by multi-well spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50075952(CHEMBL3415804)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50381960(CHEMBL2022927)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50358012(CHEMBL1651055)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50075959(CHEMBL3415795)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM218829(1,4-Bis(2-pentanoylimino-5-(2-methoxy-2-oxoethylid...)
Affinity DataIC50: 1nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049682(2-Methoxy-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50075947(CHEMBL3415817)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MAO A in mouse GL26 cells preincubated for 20 mins followed by 14C-labeled 5-hydroxytryptamine addition and measured after 20 mins by s...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50367064(CHEMBL1204338)
Affinity DataIC50: 1nMAssay Description:Compound was tested in vitro for inhibition of rat brain mitochondrial monoamine oxidase A.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM10989((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...)
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MAO-A (unknown origin) expressed in mouse GL26 cells using 14C 5-hydroxytryptamine as substrate pre-incubated for 20 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50179019(3-benzyl-N-(2-morpholinoethyl)quinoxalin-2-amine |...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat liver mitochondria MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50075974(CHEMBL3415783)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50075965(CHEMBL3415613)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50105417(CHEMBL1089 | Nardil | Phenethyl-hydrazine | PHENEL...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells using p-tyramine as substrate preincubated for 15 mins followed by substrate addition fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50073539(CHEMBL3408926)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50073539(CHEMBL3408926)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50073512(CHEMBL3408911)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50179021(3-(4-chlorobenzyl)-N-(2-morpholinoethyl)quinoxalin...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat liver mitochondria MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50075996(CHEMBL3415611)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of N-terminal FLAG-tagged human recombinant MAO-A expressed in Sf9 cells preincubated for 15 mins followed by MAO substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049666(5-(10,10-Dioxo-10H-10lambda*6*-phenoxathiin-2-yl)-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049671(2-Methyl-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049701(3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-10,10-dioxo-10H...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049704(2-(5-Methyl-[1,3,4]oxadiazol-2-yl)-10,11-dioxa-dib...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against Monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049703(6-(2-Methyl-2H-tetrazol-5-yl)-10,10-dioxo-2-propox...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50049686(2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-diox...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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