Compile Data Set for Download or QSAR
Report error Found 151 of ic50 data for polymerid = 3423,50001915
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28428((2R,3R,4S,5R)-2-(6-amino-8-methyl-9H-purin-9-yl)-5...)
Affinity DataIC50: 5nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50368644(Sardomozide chloride | CHEMBL1202793)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046206(2,2'-bipyridine-6,6'-dicarboximidamide | CHEMBL151...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046197(4-{3-[(Z)-amino(imino)methyl]phenyl}pyrimidine-2-c...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28421((2R,3R,4S,5R)-2-(6-amino-8-methyl-9H-purin-9-yl)-5...)
Affinity DataIC50: 7nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50368645(CHEMBL1202792)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28427((2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-...)
Affinity DataIC50: 11nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28429((2R,3R,4S,5R)-2-(6-amino-8-ethyl-9H-purin-9-yl)-5-...)
Affinity DataIC50: 15nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28430((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-({[4-(am...)
Affinity DataIC50: 18nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046189((2E)-2-{3-[(Z)-amino(imino)methyl]benzylidene}hydr...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28425((2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-...)
Affinity DataIC50: 49nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28431((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-({[2-(am...)
Affinity DataIC50: 55nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046196(CGP-40215 | 3-((E)-{[(Z)-((2E)-2-{3-[(E)-amino(imi...)
Affinity DataIC50: 61nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046200((2E)-2-(1-{3-[(E)-amino(imino)methyl]phenyl}ethyli...)
Affinity DataIC50: 66nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046190(6-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50: 84nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28423((2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-...)
Affinity DataIC50: 86nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046193((2E)-2-(1-{3-[(E)-amino(imino)methyl]phenyl}propyl...)
Affinity DataIC50: 88nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046210(6-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046209((2E)-2-{3-[(E)-amino(imino)methyl]benzylidene}-N'-...)
Affinity DataIC50: 92nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046207(6-((E)-{[(E)-[(2E)-2-({6-[(E)-amino(imino)methyl]p...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046191((2E)-2-{3-[(E)-amino(imino)methyl]benzylidene}-N'-...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28436(3-({[(2R,3S,4R,5R)-5-(6-amino-8-methyl-9H-purin-9-...)
Affinity DataIC50: 170nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046204(4,4'-bipyridine-2,2'-dicarboximidamide | CHEMBL433...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046203(3-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046202(6-((E)-{[(E)-amino(hydroxyimino)methyl]hydrazono}m...)
Affinity DataIC50: 240nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046195(4-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50: 330nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28432(3-({[(2R,3S,4R,5R)-5-(6-amino-8-methyl-9H-purin-9-...)
Affinity DataIC50: 400nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046194(4-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50: 530nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28452((2R,3R,4S,5R)-2-(6-amino-8-methyl-9H-purin-9-yl)-5...)
Affinity DataIC50: 600nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046212(1,1'-biphenyl-3,3'-dicarboximidamide | CHEMBL15062...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046192(6-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}meth...)
Affinity DataIC50: 670nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50046201(Mitoguazone | (2E)-2-((2E)-2-{[(E)-amino(imino)met...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50044330((2Z)-2-((2E)-2-{[(E)-amino(imino)methyl]hydrazono}...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28437(3-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-d...)
Affinity DataIC50: 1.50E+3nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28454({[(2S,3S,4R,5R)-5-(6-amino-8-methyl-9H-purin-9-yl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046205(2,2'-bipyridine-4,4'-dicarboximidamide | CHEMBL151...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28433(3-({[(2R,3S,4R,5R)-5-(6-amino-8-ethyl-9H-purin-9-y...)
Affinity DataIC50: 4.00E+3nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50368643(CHEMBL1202794)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28435(3-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-d...)
Affinity DataIC50: 7.00E+3nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50254958(CHEMBL4075752)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AdoMetDC expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28453((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-[(dimeth...)
Affinity DataIC50: 9.00E+3nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50281292(2-amino-4-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against AdoMet-DC from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50046211(2-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)p...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28455({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihy...)
Affinity DataIC50: 1.50E+4nMAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50046208(3-((E)-{[(E)-amino(imino)methyl]hydrazono}methyl)b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50254815(CHEMBL4104060)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AdoMetDC expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50254902(CHEMBL4079242)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AdoMetDC expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50254905(CHEMBL4094809)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AdoMetDC expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50254955(CHEMBL4094762)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AdoMetDC expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM50255018(CHEMBL4079196)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AdoMetDC expressed in Escherichia coli BL21/DE3 cells at pH 7.2 by RapidFire-MS-based enzyme a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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