Compile Data Set for Download or QSAR
Report error Found 149 of ic50 data for polymerid = 3035,50004527
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50: 0.0820nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392401(CHEMBL2151642)
Affinity DataIC50: 0.110nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50: 0.110nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50: 0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50: 0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107307(US8592379, 19)
Affinity DataIC50: 0.120nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392412(CHEMBL2151653)
Affinity DataIC50: 0.130nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392405(CHEMBL2151646)
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392405(CHEMBL2151646)
Affinity DataIC50: 0.170nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392409(CHEMBL2151650)
Affinity DataIC50: 0.190nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392413(CHEMBL2151654)
Affinity DataIC50: 0.190nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392412(CHEMBL2151653)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392413(CHEMBL2151654)
Affinity DataIC50: 0.220nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26347((2R,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50: 0.240nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107314(US8592379, 37 | US8592379, 36)
Affinity DataIC50: 0.240nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392409(CHEMBL2151650)
Affinity DataIC50: 0.240nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392401(CHEMBL2151642)
Affinity DataIC50: 0.260nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392414(CHEMBL2151655)
Affinity DataIC50: 0.280nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392411(CHEMBL2151652)
Affinity DataIC50: 0.280nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392414(CHEMBL2151655)
Affinity DataIC50: 0.280nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392411(CHEMBL2151652)
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392408(CHEMBL2151649)
Affinity DataIC50: 0.430nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392406(CHEMBL2151647)
Affinity DataIC50: 0.430nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392408(CHEMBL2151649)
Affinity DataIC50: 0.460nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392406(CHEMBL2151647)
Affinity DataIC50: 0.490nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392404(CHEMBL2151645)
Affinity DataIC50: 0.510nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392403(CHEMBL2151644)
Affinity DataIC50: 0.610nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392410(CHEMBL2151651)
Affinity DataIC50: 0.700nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26338(N-[(4-fluorophenyl)carbonyl]-L-phenylalanylglycyl-...)
Affinity DataIC50: 0.710nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107306(US8592379, 1)
Affinity DataIC50: 0.710nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26338(N-[(4-fluorophenyl)carbonyl]-L-phenylalanylglycyl-...)
Affinity DataIC50: 0.710nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392407(CHEMBL2151648)
Affinity DataIC50: 0.830nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392407(CHEMBL2151648)
Affinity DataIC50: 0.860nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392410(CHEMBL2151651)
Affinity DataIC50: 0.890nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26340((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50: 1.20nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107308(US8592379, 20)
Affinity DataIC50: 1.20nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392403(CHEMBL2151644)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392402(CHEMBL2151643)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392404(CHEMBL2151645)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392402(CHEMBL2151643)
Affinity DataIC50: 3.30nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-piper...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320821(N-{4-[3-(beta-Alanylamino)phenyl]-3-cyano-6-(4-flu...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]metastin(40-54) from human GPR54 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320821(N-{4-[3-(beta-Alanylamino)phenyl]-3-cyano-6-(4-flu...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322292(N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(glyc...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26341((2E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50: 4.60nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107309(US8592379, 21)
Affinity DataIC50: 4.60nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322307(N-[3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-{3-[(N-m...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKiSS-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26345((2R,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50: 5.70nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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