Compile Data Set for Download or QSAR
Report error Found 4688 of ic50 data for polymerid = 2939,50007102
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50201033(CHEMBL3924812)
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of 1 to 324 residues truncated c-Raf (unknown origin) expressed in baculovirus infected Sf9 insect cells using full length biotinylated ME...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50201031(CHEMBL3961999)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of 1 to 324 residues truncated c-Raf (unknown origin) expressed in baculovirus infected Sf9 insect cells using full length biotinylated ME...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202851(US9694016, 829 | US9242969, 204 | US10245267, Exam...)
Affinity DataIC50: 0.0390nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202851(US9694016, 829 | US9242969, 204 | US10245267, Exam...)
Affinity DataIC50: 0.0400nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87817(US9694016, 847 | US10245267, Example 847 | US10709...)
Affinity DataIC50: 0.0400nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202851(US9694016, 829 | US9242969, 204 | US10245267, Exam...)
Affinity DataIC50: 0.0400nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87817(US9694016, 847 | US10245267, Example 847 | US10709...)
Affinity DataIC50: 0.0400nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202729(US9694016, 75 | US9242969, 75 | US10245267, Exampl...)
Affinity DataIC50: 0.0560nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202729(US9694016, 75 | US9242969, 75 | US10245267, Exampl...)
Affinity DataIC50: 0.0560nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202729(US9694016, 75 | US9242969, 75 | US10245267, Exampl...)
Affinity DataIC50: 0.0600nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202729(US9694016, 75 | US9242969, 75 | US10245267, Exampl...)
Affinity DataIC50: 0.0600nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202850(US9694016, 824 | US9242969, 203 | US10245267, Exam...)
Affinity DataIC50: 0.0650nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202850(US9694016, 824 | US9242969, 203 | US10245267, Exam...)
Affinity DataIC50: 0.0700nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM88127(US9694016, 1162 | US10245267, Example 1162 | US107...)
Affinity DataIC50: 0.0700nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202850(US9694016, 824 | US9242969, 203 | US10245267, Exam...)
Affinity DataIC50: 0.0700nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM88127(US9694016, 1162 | US10245267, Example 1162 | US107...)
Affinity DataIC50: 0.0700nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87369(US9694016, 704 | US10245267, Example 704 | US10709...)
Affinity DataIC50: 0.0800nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87741(US9694016, 777 | US10245267, Example 777 | US10709...)
Affinity DataIC50: 0.0800nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87829(US9694016, 857 | US10245267, Example 857 | US10709...)
Affinity DataIC50: 0.0800nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87369(US9694016, 704 | US10245267, Example 704 | US10709...)
Affinity DataIC50: 0.0800nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87741(US9694016, 777 | US10245267, Example 777 | US10709...)
Affinity DataIC50: 0.0800nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87829(US9694016, 857 | US10245267, Example 857 | US10709...)
Affinity DataIC50: 0.0800nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81120(US9694016, 413 | US10245267, Example 413 | US10709...)
Affinity DataIC50: 0.0900nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202697(US9242969, 43 | US10245267, Example 42 | US1070971...)
Affinity DataIC50: 0.0900nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM88121(US9694016, 1157 | US10245267, Example 1157 | US107...)
Affinity DataIC50: 0.0900nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM88121(US9694016, 1157 | US10245267, Example 1157 | US107...)
Affinity DataIC50: 0.0900nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202696(US9694016, 42 | US9242969, 42 | US10245267, Exampl...)
Affinity DataIC50: 0.0900nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81120(US9694016, 413 | US10245267, Example 413 | US10709...)
Affinity DataIC50: 0.0900nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202830(US9694016, 177 | US9242969, 177 | US10245267, Exam...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM77771(US9694016, 231 | US10245267, Example 231 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM77866(US9694016, 307 | US10245267, Example 307 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81176(US9694016, 475 | US10245267, Example 475 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81177(US9694016, 476 | US10245267, Example 476 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81181(US9694016, 480 | US10245267, Example 480 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81185(US9694016, 484 | US10245267, Example 484 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM81235(US9694016, 519 | US10245267, Example 519 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM84273(US9694016, 561 | US10245267, Example 561 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM84292(US9694016, 580 | US10245267, Example 580 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM86368(US9694016, 659 | US10245267, Example 659 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87373(US9694016, 708 | US10245267, Example 708 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87785(US9694016, 820 | US10245267, Example 820 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87794(US9694016, 830 | US10245267, Example 830 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87803(US9694016, 837 | US10245267, Example 837 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87818(US9694016, 848 | US10245267, Example 848 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87824(US9694016, 854 | US10245267, Example 854 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM87846(US9694016, 871 | US10245267, Example 879 | US10709...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202656(US9694016, 1 | US9242969, 1 | US10245267, Example ...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202658(US9694016, 3 | US9242969, 3 | US10245267, Example ...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202673(US9694016, 18 | US9242969, 18 | US10245267, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM202682(US9694016, 27 | US9242969, 27 | US10245267, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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