Compile Data Set for Download or QSAR
Report error Found 69 of ic50 data for polymerid = 2917,5910,50000041,50002693
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503849(CHEMBL4590466)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189833((S)-N-butyl-3-((S)-2-(4-fluorophenylsulfonamido)-3...)
Affinity DataIC50: 21nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25891((2S)-2-[(5-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503846(CHEMBL4540394)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358153(CHEMBL1921830)
Affinity DataIC50: 30nMAssay Description:Inhibition of calpain-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358153(CHEMBL1921830)
Affinity DataIC50: 30nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503847(CHEMBL4574306)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50114340(N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal | (S...)
Affinity DataIC50: 49nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284777(Z-Phe-Tyr(Bu)-H | CHEMBL36969)
Affinity DataIC50: 80nMAssay Description:Compound was tested for its inhibitory activity against calpain 2More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25890((2S)-2-[(5-formylthiophen-2-yl)formamido]-3-methyl...)
Affinity DataIC50: 85nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358152(CHEMBL1921829)
Affinity DataIC50: 85nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263559(2-(2-methoxyethoxy)ethyl (S)-1-((S)-4-(cyclopropyl...)
Affinity DataIC50: 99nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25887((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263560(2-methoxyethyl (S)-1-((S)-4-(cyclopropylamino)-3,4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25889((2S)-2-[(5-formylfuran-2-yl)formamido]-3-methyl-N-...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25892((2S)-2-[(4-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284776(Z-Phe-Tyr(Me)-H | CHEMBL36904)
Affinity DataIC50: 104nMAssay Description:Compound was tested for its inhibitory activity against calpain 2More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284780(Z-Phe-Phe-H | CHEMBL36801)
Affinity DataIC50: 104nMAssay Description:Compound was tested for its inhibitory activity against Calpain 2More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25894((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189825((2S)-2-((((4-cyanophenyl)amino)thioxomethyl)amino)...)
Affinity DataIC50: 120nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263561(2-(2-(2-methoxyethoxy)ethoxy)ethyl (S)-1-((S)-4-(c...)
Affinity DataIC50: 120nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25886((2S)-2-(furan-2-ylformamido)-3-methyl-N-[(2S)-4-me...)
Affinity DataIC50: 135nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25895(methyl 5-{[(1S)-2-methyl-1-{[(2S)-4-methyl-1-oxope...)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25893((2S)-2-[(5-formyl-1-methyl-1H-pyrrol-2-yl)formamid...)
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM23866(benzyl N-[(1S)-2-methyl-1-[(1-oxo-3-phenylpropan-2...)
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50503845(CHEMBL4531762)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189832((2S)-4-methyl-2-((((4-methylphenyl)amino)thioxomet...)
Affinity DataIC50: 170nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189834((2S)-2-((((3-cyanophenyl)amino)thioxomethyl)amino)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263613(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethyl (S)-1...)
Affinity DataIC50: 170nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358155(CHEMBL1921832)
Affinity DataIC50: 180nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284779(Z-Phe-Tyr-H | CHEMBL36146)
Affinity DataIC50: 184nMAssay Description:Compound was tested for its inhibitory activity against calpain 2More data for this Ligand-Target Pair
In DepthDetails Article

TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50084650({1-[1-Formyl-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-...)
Affinity DataIC50: 184nMAssay Description:Inhibitory activity against Calpain 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189835((2S)-2-((((4-fluorophenyl)amino)thioxomethyl)amino...)
Affinity DataIC50: 190nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50263558(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)e...)
Affinity DataIC50: 190nMAssay Description:Inhibition of pig kidney m-calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189828(SNJ-1715 | 1-((S)-1-((3S)-2-hydroxy-tetrahydrofura...)
Affinity DataIC50: 190nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189827((2S)-2-((((4-methoxyphenyl)amino)thioxomethyl)amin...)
Affinity DataIC50: 200nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189822((2S)-2-((benzylamino)thioxomethyl)amino)-4-methyl-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189830((2S)-4-methyl-2-((((2-methylphenyl)amino)thioxomet...)
Affinity DataIC50: 250nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358148(CHEMBL1921825)
Affinity DataIC50: 280nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358157(CHEMBL1921834)
Affinity DataIC50: 295nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Sheep)
University of Canterbury

LigandPNGBDBM25888((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50: 315nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189831((2S)-4-methyl-2-((((3-methylphenyl)amino)thioxomet...)
Affinity DataIC50: 340nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM110185(benzyl N-[1-[(4-fluoro-3-oxo-1-phenylbutan-2-yl)am...)
Affinity DataIC50: 418nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358154(CHEMBL1921831)
Affinity DataIC50: 700nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358150(CHEMBL1921827)
Affinity DataIC50: 850nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358158(CHEMBL1921835)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358156(CHEMBL1921833)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189823((2S,3S)-3-methyl-2-(((phenylamino)thioxomethyl)ami...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Pig)
University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50189829((2S)-3-methyl-2-(((phenylamino)thioxomethyl)amino)...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of porcein kidney m calpainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358149(CHEMBL1921826)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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