Compile Data Set for Download or QSAR
Report error Found 269 of ic50 data for polymerid = 2891,8985,50000911,50007579
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215880(CHEMBL52311 | Ro-092364)
Affinity DataIC50: 22.5nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215878(CHEMBL54768 | Ro-092056)
Affinity DataIC50: 28.1nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215878(CHEMBL54768 | Ro-092056)
Affinity DataIC50: 28.1nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
In DepthDetails Article

TargetLanosterol 14-alpha demethylase(Rat)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 47nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215879(CHEMBL415943 | Ro-092435)
Affinity DataIC50: 56.3nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215883(CHEMBL53214 | Ro-092182)
Affinity DataIC50: 73.3nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Yeast)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50593137(CHEMBL5187700)
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP51 in Candida albicans SC5314 using Eburicol as substrate preincubated for 20 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215876(CHEMBL53213 | Ro-092173)
Affinity DataIC50: 83nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50011478(ITRAZOLE)
Affinity DataIC50: 85nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
In DepthDetails Article

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50215882(CHEMBL298394 | Ro-092183)
Affinity DataIC50: 86.8nMAssay Description:In vitro inhibition of cytochrome P450 lanosterol C14 demethylase in Candida albicans CY1005More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50469749(CHEMBL349069 | Ro-092127)
Affinity DataIC50: 90.3nMAssay Description:In vitro inhibition of Lanosterol 14-alpha demethylase (Candida albicans CY1005)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628721(US20230339890, Compound 1)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628724(US20230339890, Compound 76)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628725(US20230339890, Compound 100)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628729(US20230339890, Compound 124)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628730(US20230339890, Compound 2)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628731(US20230339890, Compound 27)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628733(US20230339890, Compound 77)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628735(US20230339890, Compound 125)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628755(US20230339890, Compound 128)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628756(Preparation of 2-(3,4-Dichlorophenyl)-N-[(2R)-2-Hy...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628757(US20230339890, Compound 31)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628761(US20230339890, Compound 105)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628763(Preparation of N-[(2S)-2-Hydroxy-2-(3-Pyridyl)Ethy...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628770(US20230339890, Compound 130)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628771(US20230339890, Compound 8)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628775(US20230339890, Compound 107)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628776(US20230339890, Compound 131)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628788(US20230339890, Compound 109)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628792(US20230339890, Compound 11)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628797(US20230339890, Compound 134)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628803(US20230339890, Compound 135)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628780(US20230339890, Compound 84 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628809(US20230339890, Compound 136)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628812(US20230339890, Compound 64)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628815(US20230339890, Compound 137)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628820(US20230339890, Compound 90 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628823(Preparation of 2-(3-Chloro-4-Methyl-Phenyl)-N-[(2S...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628820(US20230339890, Compound 90 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628830(US20230339890, Compound 139)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628831(Preparation of N-[(2S)-2-Hydroxy-2-(3-Pyridyl)Ethy...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628762(US20230339890, Compound 129 | US20230339890, Compo...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628834(US20230339890, Compound 67)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628820(US20230339890, Compound 90 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628837(US20230339890, Compound 140)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628838(US20230339890, Compound 18)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628843(US20230339890, Compound 141)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628766(US20230339890, Compound 32 | US20230339890, Compou...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM628849(US20230339890, Compound 142)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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