Compile Data Set for Download or QSAR
Report error Found 33 of ic50 data for polymerid = 2442,5269,50000644,50000871,50003915
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612694(CHEMBL5281742)
Affinity DataIC50: 0.885nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506040(CHEMBL4536502)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H] 3-MC from AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Zebrafish)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525571(CHEMBL4467659)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Zebrafish)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525574(CHEMBL4546269)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Zebrafish)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525570(CHEMBL4463944)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Zebrafish)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525573(CHEMBL4470684)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50439845(CHEMBL2420083)
Affinity DataIC50: 21nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Rat)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50240990(NSC-721648 | 2-(3,4-dimethoxyphenyl)-5-fluorobenzo...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosolMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240990(NSC-721648 | 2-(3,4-dimethoxyphenyl)-5-fluorobenzo...)
Affinity DataIC50: 25nMAssay Description:Binding affinity to AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Mouse)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 25nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7462(cid_5280863 | CHEMBL150 | 3,5,7-trihydroxy-2-(4-hy...)
Affinity DataIC50: 28nMAssay Description:Inhibition of aryl hydrocarbon receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50525572(CHEMBL1743245 | CH-223191)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at AhR (unknown origin) assessed as inhibition of TCDD-induced luciferase activityMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612692(CHEMBL5266911)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at AhR (unknown origin) expressed in human U87 cells assessed as inhibition of kynurenic acid-induced transactivation by Renilla/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612695(CHEMBL5271453)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Zebrafish)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50525572(CHEMBL1743245 | CH-223191)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612699(CHEMBL4303221)
Affinity DataIC50: 127nMAssay Description:Antagonist activity at AhR in human HepG2 cells assessed as inhibition of TCDD-induced receptor activation pretreated for 1 hr followed by TCDD addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612696(CHEMBL5280174)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Rat)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50612693(CHEMBL5267451)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at AhR in rat liver cytosol assessed as inhibition of TCDD-induced AhR/DNA complex formation by gel retardation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269353(CHEMBL4105559)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human AhR expressed in Saccharomyces cerevisiae W303-1A (ATCC 208352) transformed with an episomal plasmid containing a minima...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50525572(CHEMBL1743245 | CH-223191)
Affinity DataIC50: 2.43E+3nMAssay Description:Antagonist activity at AhR in human HepG2 cells assessed as inhibition of FICZ-induced AhR transcriptional activity incubated for 24 hrs by Quanti-Lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Rat)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50612693(CHEMBL5267451)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TCDD binding to rat liver cytosol AhRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: 5.20E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191436((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50: 5.40E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269354(CHEMBL1335197)
Affinity DataIC50: 7.60E+3nMAssay Description:Antagonist activity at human AhR expressed in Saccharomyces cerevisiae W303-1A (ATCC 208352) transformed with an episomal plasmid containing a minima...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612697(CHEMBL3252119)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50612698(CHEMBL5287208)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50: 1.30E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191395((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrro...)
Affinity DataIC50: 1.88E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191405((2'Z,3'E)-7-bromoindirubin-3'-oxime | CHEMBL373834)
Affinity DataIC50: 2.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191422((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimet...)
Affinity DataIC50: 2.40E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191396((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191411((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAryl hydrocarbon receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50191415((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-y...)
Affinity DataIC50: 3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed