Compile Data Set for Download or QSAR
Report error Found 1822 of ic50 data for polymerid = 239,1235,1261,1297,5406,5454,5547,6926,50002629
TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM168608(US9079834, 2)
Affinity DataIC50: 0.0190nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM60467(BDBM168607 | US9079834, 1-1)
Affinity DataIC50: 0.0300nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM60623(BDBM180165 | US9133157, 103)
Affinity DataIC50: 0.0900nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180212(US9133157, 94)
Affinity DataIC50: 0.0900nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180171(US9133157, 53)
Affinity DataIC50: 0.156nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180183(US9133157, 65)
Affinity DataIC50: 0.180nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180163(US9133157, 44)
Affinity DataIC50: 0.196nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180201(US9133157, 83)
Affinity DataIC50: 0.300nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180164(US9133157, 45 | US9133157, 102)
Affinity DataIC50: 0.308nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180119(US9133157, 8)
Affinity DataIC50: 0.310nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180211(US9133157, 93)
Affinity DataIC50: 0.310nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180203(US9133157, 85)
Affinity DataIC50: 0.330nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180206(US9133157, 88)
Affinity DataIC50: 0.330nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180204(US9133157, 86)
Affinity DataIC50: 0.340nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM168610(US9079834, 5)
Affinity DataIC50: 0.390nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM50461442(CHEMBL4225363)
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM50461431(CHEMBL4228517)
Affinity DataIC50: 0.420nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM168612(US9079834, 7)
Affinity DataIC50: 0.430nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180135(US9133157, 16)
Affinity DataIC50: 0.440nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180216(US9133157, 98)
Affinity DataIC50: 0.440nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180192(US9133157, 74)
Affinity DataIC50: 0.450nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180232(US9133157, 117)
Affinity DataIC50: 0.470nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180116(US9133157, 5)
Affinity DataIC50: 0.540nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM168609(US9079834, 4)
Affinity DataIC50: 0.590nMAssay Description:Assays for the inhibition of acute HIV infection of T-lymphoid cells were conducted in accordance with Vacca, J.P. et al, Proc. Natl. Acad. Sci. USA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180120(US9133157, 9)
Affinity DataIC50: 0.630nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180164(US9133157, 45 | US9133157, 102)
Affinity DataIC50: 0.630nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180202(US9133157, 84)
Affinity DataIC50: 0.75nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180229(US9133157, 114)
Affinity DataIC50: 0.770nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180219(US9133157, 101)
Affinity DataIC50: 0.840nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180222(US9133157, 104)
Affinity DataIC50: 0.850nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180218(US9133157, 100)
Affinity DataIC50: 0.900nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM50461430(CHEMBL4226862)
Affinity DataIC50: 1nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180215(US9133157, 97)
Affinity DataIC50: 1.23nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM50461417(CHEMBL4225028)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180175(US9133157, 57)
Affinity DataIC50: 1.32nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180147(US9133157, 28)
Affinity DataIC50: 1.45nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM50461438(CHEMBL4226921)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM180130(US9133157, 11)
Affinity DataIC50: 1.61nMpH: 5.5 T: 2°CAssay Description:The inhibition of WT HIV-1 protease was studied using the reaction of the protease (expressed in Eschericia coli) with a peptide substrate [Val-Ser-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Merck Canada

US Patent
LigandPNGBDBM50461421(CHEMBL3828596)
Affinity DataIC50: 1.70nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460896(US10774053, Compound 10 | US11352329, COMPD # 10)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460898(US10774053, Compound 12 | US11352329, COMPD # 12)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM556544(US11352329, COMPD # 17)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460904(US10774053, Compound 18 | US11352329, COMPD # 18)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460910(US10774053, Compound 24 | US11352329, COMPD # 24)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM556555(US11352329, COMPD # 28)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460917(BDBM556558 | US10774053, Compound 31)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460918(US10774053, Compound 32 | US11352329, COMPD # 32)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460922(US10774053, Compound 36 | US11352329, COMPD # 36)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460924(US10774053, Compound 38 | US11352329, COMPD # 38)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetGag-Pol polyprotein(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM460925(US10774053, Compound 39 | US11352329, COMPD # 39)
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

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